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Nexpro 40mg
Nexpro 40mg
Esomeprazole
Price range: $8.00 through $24.00
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| Active Ingredient (Generic Name) | Indication | US Brand | Manufacturer | Packaging | Strength | Delivery Time |
|---|---|---|---|---|---|---|
| Esomeprazole 40 mg | GERD, erosive oesophagitis, ulcer prophylaxis, Z‑E syndrome | Nexium® 40 mg | Torrent Pharma, India (Est. 1959) | 15 tablets / strip | 40 mg | 6 – 15 days |
✨ Quick Facts
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Brand: Nexpro 40 (high‑strength PPI)
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Form: Enteric‑coated, easy‑swallow 9 mm tablet
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pH coverage: Maintains gastric pH > 4 for ≈ 20 h after day 5 dosing
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India MRP: ₹ 190 / strip (~$2.30) Zeelab Pharmacy
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Savings vs US generic: 87 % cheaper per mg Drugs.com
⚙️ How Nexpro 40 Works
| Esomeprazole 40 mg | |
|---|---|
| Class | Proton‑pump inhibitor |
| Mechanism | Irreversible blockade of the H⁺/K⁺‑ATPase on parietal cells |
| Onset | Acid output ↓ 50 % within 1 h; steady‑state by day 4 |
| Bioavailability | ↑ to ~90 % after repeat dosing Access Data |
| Key benefit | Greater AUC and night‑time acid control vs omeprazole |
🩺 Doctor Insight
“For patients with grade B‑D esophagitis, I upgrade to esomeprazole 40 mg once daily. Nexpro’s cost advantage allows compliance without trade‑offs in dissolution or GMP quality.”
— Dr Vinay Kapoor, DM (GI), Fortis Mumbai
🌍 Buying & Import Guide
🌎 USA
| Details | |
|---|---|
| Regulation | Rx‑only; personal import ≤90‑day supply |
| Local cost | Generic ≈ $0.60 / cap (30‑count) Drugs.com |
| Import steps | Prescription + CBP form 3299; declare “non‑controlled Rx for personal therapy.” |
🇬🇧 UK
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Prescription‑only medicine (POM).
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Import under “named‑patient” scheme with cover letter.
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Pay 0 % VAT when declared as personal medication < £135.
🇦🇺 Australia
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Schedule 4.
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3‑month personal import allowed (TGA Section 19A).
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Declare on Incoming Passenger Card if carrying.
💸 Three‑Month Price Comparison (90 tabs)
| Source | Cost | Saving vs US brand |
|---|---|---|
| US brand Nexium® | $270 | – |
| US generic | $54 | 80 % |
| Nexpro 40 import | $13.70 | 95 % |
🗓️ Indications & Doses
| Condition | Dose (Adults) | Duration |
|---|---|---|
| Erosive GERD | 40 mg OD | 4–8 weeks |
| Symptomatic GERD | 20–40 mg OD | On‑demand / maintenance |
| H. pylori triple | 40 mg BD | 14 days |
| Zollinger‑Ellison | 40 mg BID → titrate | Long‑term |
Take ≥30 min pre‑meal with 200 ml water.
🧭 Torrent Pharma Snapshot
| Founded | 1959 by U. N. Mehta Wikipedia |
| Headquarters | Ahmedabad, India |
| Global presence | 40 + countries, 2 000 + registrations |
| Certifications | US‑FDA, EMA, TGA, WHO‑GMP |
🛡️ Safety Matrix
| Frequency | Adverse Effect | Monitoring / Mitigation |
|---|---|---|
| Common | Headache, mild diarrhoea | Usually self‑limiting |
| Uncommon | Hypomagnesaemia (≥3 mo) | Serum Mg²⁺ every 6 mo nhs.uk |
| Rare | Wrist/hip fractures (>1 y) | DEXA in high‑risk >50 y remedy.bnssg.icb.nhs.uk |
| Drug ⚠ | ↓ clopidogrel efficacy | Prefer ticagrelor or de‑escalate SPS – Specialist Pharmacy Service |
Deprescribing tip: Review need annually; step down to 20 mg or on‑demand once symptoms controlled. NHS PPI algorithm 2024 guides this process remedy.bnssg.icb.nhs.uk.
🌡️ Storage
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15 – 30 °C, < 60 % RH.
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Keep desiccant sachet; avoid splitting strip to deter moisture ingress.
🔗 Related Indian Brands (Internal Links)
| 🟢 Name | Snapshot |
|---|---|
| Sompraz 40 | Sun Pharma; identical strength with enteric micro‑pellets |
| Pan 40 | Alkem classic pantoprazole for cost‑focused users |
| Lanzol 30 | Lansoprazole; faster onset within 60 min |
| Omez 40 | Dr Reddy’s omeprazole high‑dose alternative |
| Rabicip 20 | Rabeprazole; acid rebound lowest among PPIs |
📚 Authoritative Sources
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U.S. FDA Nexium® label, 40 mg (2024 rev) Access Data
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Drugs.com Esomeprazole price guide, 40 mg (accessed Apr 2025) Drugs.com
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NHS Medicines A–Z: Esomeprazole safety & monitoring nhs.uk
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BNSSG 2024 PPI de‑prescribing algorithm remedy.bnssg.icb.nhs.uk
❓ FAQ
Can I halve Nexpro 40 tablets?
No—enteric coat must stay intact for duodenal release.
Safe in pregnancy?
Category B; short courses acceptable under OB guidance.
Rebound acid on stopping?
Taper to 20 mg OD for 2 weeks, then step off to H₂‑blocker if needed.
🔑 Key Takeaways
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High‑strength acid suppression: ideal for severe GERD & Z‑E syndrome.
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Massive cost edge when imported from India—up to 95 % savings.
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Annual safety review essential: magnesium, bone health, infection risk.
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Torrent Pharma’s 60‑year pedigree ensures global GMP compliance.
Additional Information
| Active | Esomeprazole |
|---|---|
| Tablets | 30, 60, 90 |
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