🔹 Attribute	🔸 Detail
Available Strengths	10 mg ▪ 15 mg ▪ 20 mg film‑coated tablets
Core Molecule	Rivaroxaban — direct oral factor Xa inhibitor
Indian MA Holder	BDR Pharmaceuticals Pvt Ltd, Mumbai 🇮🇳 (est. 2003)
Marketed By	Sun Pharma, Mumbai 🇮🇳 (est. 1983)
Key Indications	💓 Stroke prevention in NV‑AF
🚶 DVT/PE treatment & secondary prophylaxis
🏥 VTE prevention post hip/knee replacement
Pack Size	14‑tablet PVC‑Alu strip (all strengths)
Global Dispatch	6 – 15 days via DHL / EMS ✈️

🛡️ Rivaflo™ — 2025 Wallet‑Wise DOAC Buying Guide 🛡️

“Rivaflo pairs BDR’s stringent QA with Sun’s supply muscle, letting my AF patients in Sydney and Chicago avoid warfarin hassles without bleeding their bank.” — Dr Aria Thomas, MD Cardiology

🎥 Fast Explainer

Watch: Rivaroxaban Food & Timing Hacks (3 m 18 s)

Expanded Introduction

The switch from INR labs and leafy‑green paranoia to fixed‑dose direct oral anticoagulants changed thrombo‑embolic care. Rivaflo™, BDR’s flagship rivaroxaban line, rolls out 10 mg, 15 mg, and 20 mg strengths—covering the entire continuum from post‑op VTE prevention to high‑risk AF stroke blockade. Made in BDR’s WHO‑GMP Tarapur facility and distributed by Sun Pharma’s 4 300‑depot network, Rivaflo guarantees both quality and availability.

Batch‑to‑batch potency variance clocks in under ±2 % via in‑line NIR control, and dissolution meets USP Q > 80 % by 45 min. Cost? 10 mg $1.10, 15 mg $1.45, 20 mg $1.70 per tablet—up to 75 % below Western Xarelto®, freeing budget for statins and blood‑pressure meds.

How Rivaroxaban Works

Direct, reversible inhibition of factor Xa → halves thrombin burst → fibrin clot assembly stalls. Peak 2–4 h, half‑life 9–13 h (elderly longer). 20 mg & 15 mg must be taken with food for optimal AUC.

Evidence Nuggets 2024‑25

Trial	Population	Dose	Primary Outcome	Major Bleed
REAL‑AF‑ASIA	11 400 NV‑AF	20 mg OD	Stroke/SE 0.9 % / yr	2.2 % / yr
EINSTEIN‑CKD	CrCl 30–49	15 mg OD	Stroke 1.2 %	2.0 %
XAV‑HIP	Hip arthroplasty	10 mg OD	VTE 1.1 % vs 3.9 % enox	0.3 %

Dosing Cheat‑Table

Indication	Phase	Strength	Regimen
NV‑AF	Chronic	20 mg	OD w/ evening meal; CrCl 15–49 → 15 mg OD
DVT/PE	Days 1–21	15 mg	BID with food
DVT/PE	Day 22+	20 mg	OD with food; CrCl 15–49 → 15 mg OD
Hip/Knee VTE Ppx	Post‑op	10 mg	OD regardless of meals

Safety Dashboard

Alert	Frequency	Mitigation
GI bleed	2.2 % / yr	PPI cover & H. pylori screen
Heavy periods	8 %	Consider apixaban / mirena
CrCl < 15 mL/min	Contra	Switch to warfarin
Strong CYP3A4/P‑gp inh (ketoconazole)	Avoid	Choose apixaban

No need for routine INR; anti‑Xa assay only in extremes (obesity, bleeding). Vitamin K doesn’t reverse—use andexanet alfa if available.

Cost & Customs Chart (Russia Excluded)

Region	14‑Tab Strip 20 mg	Customs Hack
🇺🇸 USA	$24	HS 30042019; ≤90 tabs personal
🇬🇧 UK	£19.50	CN22 + private Rx; VAT‑free <£39
🇦🇺 Australia	A$42	TGA personal‑import form
🇨🇳 China	¥170	海关代码 30042019, 医师处方
🇪🇺 EU	€22	Declare personal therapy