🔬 Active Ingredient (Generic Name):	Naproxen
💊 Indication:	Pain Management, Inflammation, Osteoarthritis, Rheumatoid Arthritis, Dysmenorrhea
🇺🇸 US Brand:	Naprosyn
🏭 Manufacturer:	RPG Life Sciences Ltd. (Founded: 1983)
📦 Packaging:	15 Tablets per Strip
🧪 Strength:	250 mg
🚚 Delivery Time:	6 To 15 days

🌿 What is Naproxen 250 mg (Naprosyn)?

Naprosyn 250 mg contains Naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that non-selectively inhibits cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain and inflammation. This lower-dose formulation provides flexible dosing options for both acute and chronic conditions, offering symptom relief with a reduced risk of gastrointestinal side effects compared to higher-dose regimens.

🧬 Chemical Properties and Mechanism of Action

Attribute	Details
Chemical Formula	C14H14O3
Molecular Weight	230.26 g/mol
Bioavailability	~95%
Metabolism	Hepatic (CYP1A2)
Elimination Half-Life	12–17 hours

Naproxen works by blocking COX-mediated conversion of arachidonic acid to prostaglandins, leading to reduced inflammation, pain, and fever.

💡 Indications & Usage

✅ Osteoarthritis & Rheumatoid Arthritis: Management of pain, stiffness, and inflammation in chronic joint disorders.

✅ Acute Musculoskeletal Pain: Relief of strains, sprains, and other acute soft tissue injuries.

✅ Dysmenorrhea: Alleviates menstrual cramps and associated discomfort.

✅ Gout Flares & Ankylosing Spondylitis: Symptomatic relief during acute episodes.

💊 Dosage Recommendations

Condition	Dosage Guidance
Mild to Moderate Pain & Dysmenorrhea	250 mg every 6–8 hours as needed, up to 1,250 mg/day
Osteoarthritis & Rheumatoid Arthritis	250–500 mg twice daily
Acute Gout Flares	500 mg initial dose, then 250 mg every 8 hours as required

Always take with food or milk to minimize gastrointestinal irritation. Dosage should be individualized based on clinical response and tolerability.

🩺 Storage and Handling

Store at controlled room temperature (20°C–25°C).
Keep in original packaging to protect from moisture and light.
Keep out of reach of children.

⚠️ Warnings & Side Effects

Common Adverse Effects:

Gastrointestinal discomfort, indigestion, heartburn
Headache, dizziness
Edema

Serious Risks:

Gastrointestinal bleeding or ulceration
Renal impairment
Increased cardiovascular risk (e.g., myocardial infarction, stroke)

Use the lowest effective dose for the shortest duration necessary to minimize risks. Monitor renal function, blood pressure, and GI symptoms during prolonged therapy.

🌐 How to Purchase in Key Markets

✅ United States: Lower doses available OTC; 250 mg requires prescription. Branded as Naprosyn.

✅ United Kingdom: Prescription-only; available as generic Naproxen.

✅ Australia: Prescription necessary; import allowed with valid prescription and TGA approval.

Import from India:

Buying Naprosyn 250 mg from India can offer cost savings. Ensure compliance with local importation laws and obtain a valid prescription before ordering.

🔗 Internal Links to Related Medications

Paracetamol 500 mg – Analgesic & antipyretic.
Diclofenac 50 mg – NSAID for pain & inflammation.
Pain-O-Soma 500 mg – Carisoprodol muscle relaxant.
Flexura 400 mg – Metaxalone for muscle spasm relief.
Ibugesic 400 mg – Ibuprofen for pain management.

🎥 Educational Video on Naproxen

Enhance your understanding of Naproxen’s pharmacology and clinical uses:

👨‍⚕️ Expert Commentary: Dr. Meera Singh, Rheumatologist

“Naproxen’s reliability and extended half-life make it a cornerstone in NSAID therapy. The 250 mg dosage balances efficacy with safety, particularly for patients at higher risk for GI side effects.”