🔬 Active Ingredient (Generic Name):	Sumatriptan Succinate
💊 Indication:	Acute Migraine Treatment
🇺🇸 US Brand:	Imitrex
🏭 Manufacturer:	Sun Pharmaceutical Industries Ltd. (Founded: 1983)
📦 Packaging:	1 Tablet per Strip
🧪 Strengths:	50 mg, 100 mg
🚚 Delivery Time:	6–15 days

🌿 What is Sumatriptan (Suminat)?

Suminat contains Sumatriptan, a selective 5-HT1B/1D receptor agonist for acute migraine relief. It works by constricting dilated cranial blood vessels and inhibiting pro-inflammatory neuropeptide release, thus alleviating headache, photophobia, and nausea.

Clinical trials demonstrate that Suminat provides significant pain relief within 30–60 minutes and sustained benefit at two hours, enhancing patient functionality during attacks. Its safety and rapid onset make it a cornerstone in acute migraine management.

For full prescribing information and safety data, refer to the FDA label for Imitrex and the Drugs.com monograph. Additional references include the NHS Medicines A–Z and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C14H21N3O2S
Molecular Weight	295.4 g/mol
Bioavailability	~14% (oral)
Metabolism	Hepatic (MAO-A)
Half-Life	~2 hours

Sumatriptan’s vasoconstrictive effect targets migraine pathophysiology, offering rapid symptomatic relief.

💡 Indications & Dosing

Strength	Dose
50 mg	50 mg at migraine onset; may repeat after 2 hours (max 200 mg/day)
100 mg	100 mg at onset; may repeat once after 2 hours (max 200 mg/day)

Take with water at first sign of attack. Do not exceed 200 mg in 24 hours.

⚠️ Warnings & Side Effects

Common:

Sensations of pressure or tightness
Flushing, dizziness
Fatigue, somnolence

Serious:

Coronary vasospasm (angina, MI)
Cerebral hemorrhage
Serotonin syndrome (with other serotonergics)

Contraindicated in cardiovascular disease; monitor chest symptoms closely.

🏥 Storage Instructions

Store at 20–25°C away from moisture. Keep in blister until use. Store out of reach of children.

🌐 Global Availability & Purchasing

USA: Prescription-only (Imitrex).
UK & Europe: Prescription required; generics available.
Australia: Prescription and TGA approval needed.

Import from India can reduce cost; ensure valid prescription and regulatory compliance.

🔗 Related Migraine Therapies

Zomig 2.5 mg – Zolmitriptan.
Maxalt 10 mg – Rizatriptan.
Relpax 40 mg – Eletriptan.
Migrainege – Sumatriptan nasal spray.
Propranolol 40 mg – Migraine prophylaxis.

🎥 Educational Video on Sumatriptan

👨‍⚕️ Expert Commentary: Dr. Maya Singh, Neurologist

“Sumatriptan is a first-line acute migraine therapy due to its rapid onset and proven effectiveness. Suminat’s formulation ensures consistent relief for patients.”