Neostigmine

✨ Neostigmine Bromide, a potent cholinesterase inhibitor, plays a critical role in modern medicine by restoring neuromuscular function and treating conditions such as myasthenia gravis, postoperative urinary retention, and paralytic ileus. With rising global demand for affordable, high-quality pharmaceuticals, many healthcare providers and patients turn to reliable Indian manufacturers—like Tablets India Ltd—for cost-effective Neostigmine Bromide tablets and injectables.

🔵 Active Ingredient & Chemical Composition

🟠 Manufacturer Profile

• ▸ Tablets India Ltd: founded 1938 by Sri Krishna Jhaver tabletsindia.com

• ▸ Divisions, export JVs

• ▸ USDMF/GMP status

🔴 Indications & Mechanism of Action

• ▸ Myasthenia gravis, ileus, urinary retention, anesthesia reversal

• ▸ How cholinesterase inhibition ↑acetylcholine

🟡 How to Buy Neostigmine Bromide

• ✣ USA: Prostigmin® availability; FDA prescription; link to FDA monograph verification.fda.gov.ph

• ✣ UK: NHS guidance; how to request via GP or import license

• ✣ Australia: PBS status; TGA import rules

• ✣ Import from India: customs clearance; courier tips

🟣 Pricing & Packaging

• ◆ Table comparing prices (₹ vs USD vs GBP vs AUD)

• ◆ Packaging options: tablets vs injection

🟢 Dosage & Administration

• ✱ Table by indication:

  Indication	Oral Dose (mg)	IV/IM Dose (mg)
  Myasthenia gravis	15–30 mg every 8 hr	0.5–2 mg titrated
  Reversal of blockade	—	0.04–0.07 mg/kg
  Paralytic ileus/urine retention	0.5–1 mg every 2 hr	—

• ✱ Administration tips

🔵 Storage & Handling

• ▸ Temperature, light protection

• ▸ Shelf-life, refrigerator recommendations

🟠 Side Effects & Precautions

• ✦ Table or bullet icons for:
  • Nausea, cramps, diarrhea
  • Bradycardia, hypotension
  • Increased secretions, miosis
  • Precautions in asthma/cardiac disease

🔴 Doctor’s Expert Review

• ✱ Dr. Anil Mehta, MD (Neurology):

  • Bio (short)

  • Clinical insights on efficacy and safety

🟡 Internal Links to Related Indian-Brand Medicines

• ◆ 🟩 Pyridostigmine Bromide (Cipla’s Piridost) – for chronic myasthenia gravis

• ◆ 🟦 Donepezil (Donexil by Cipla) – Alzheimer’s cholinesterase inhibitor

• ◆ 🟧 Rivastigmine (Rivotex by Sun Pharma) – dementia therapy

• ◆ 🟥 Galantamine (Gallimen by Intas) – mild-moderate Alzheimer’s

• ◆ 🟨 Distigmine Bromide (Ubrexin by Dr. Reddy’s) – urinary retention

🔵 External Authoritative Links

• • FDA – drug label & monograph

• • WHO – essential medicines list

• • NHS – patient information

• • Drugs.com – comprehensive drug data