🔬 Active Ingredient (Generic Name):	Memantine Hydrochloride
💊 Indication:	Moderate to Severe Alzheimer’s Disease
🇺🇸 US Brand:	Namenda
🏭 Manufacturer:	Sun Pharmaceutical Industries Ltd. (Founded: 1993)
📦 Packaging:	10 Tablets per Strip
🧪 Strength:	10 mg
🚚 Delivery Time:	6–15 days

🌿 Understanding Memantine 10 mg (Admenta)

Admenta provides 10 mg of Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist approved for moderate to severe Alzheimer’s disease. By regulating glutamatergic activity, Memantine helps protect neurons from excitotoxic damage and improves cognitive and functional outcomes.

In clinical trials, patients on 10 mg daily showed slowed cognitive decline and better daily living performance compared to placebo. Unlike cholinesterase inhibitors, Memantine targets glutamate pathways, offering an alternative mechanism that can be combined with other therapies.

For full prescribing guidelines and safety details, see the FDA label for Namenda, the Drugs.com monograph, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C12H21NN2O
Molecular Weight	215.7 g/mol
Bioavailability	~100%
Metabolism	Minimal hepatic
Half-Life	60–80 hours

Memantine’s uncompetitive antagonism at NMDA receptors prevents excessive Ca²⁺ influx, reducing neurodegeneration.

💡 Indication & Dosing Strategy

Condition	Dose
Alzheimer’s Disease (Moderate–Severe)	Start 5 mg once daily; increase by 5 mg weekly to 20 mg daily (10 mg twice daily)

Administer morning and evening. Adjust for renal impairment (CrCl <30 mL/min).

⚠️ Precautions & Adverse Effects

Common Adverse Effects:

Dizziness, headache
Constipation, confusion
Hypertension

Serious (rare):

Seizures
Hallucinations, psychosis

Monitor renal function and mental status. Titrate slowly to reduce CNS side effects.

🏥 Storage Guidelines

Keep Admenta at 20–25°C in original blister pack, protected from moisture and excessive heat.

🌐 Availability & Purchasing

USA: Prescription-only (Namenda); ER and generic forms available.
UK & EU: Prescription required; generics common.
Australia: Prescription and TGA import approval required.

Import from India can lower costs; ensure valid prescription and regulatory compliance.

🔗 Related Alzheimer’s Therapies

Donepezil 10 mg – cholinesterase inhibitor.
Galantamine 8 mg – cholinesterase inhibitor.
Rivastigmine 3 mg – dual cholinesterase inhibitor.
Memantine ER 28 mg – extended-release option.
Vitamin E 400 IU – antioxidant adjunct.

🎥 Educational Video on Memantine

👩‍⚕️ Expert Insight: Dr. Ritu Kapoor, Geriatrician

“Memantine 10 mg offers neuroprotective benefits in moderate to severe Alzheimer’s. It’s well-tolerated and can complement cholinesterase inhibitors for enhanced cognitive outcomes.”