✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Carbamazepine
💊 Indication:	Epilepsy (Partial & Generalized Tonic-Clonic Seizures), Trigeminal Neuralgia
🇺🇸 US Brand:	Tegretol
🏭 Manufacturer:	Sun Pharmaceutical Industries Ltd. (Founded: 1993)
📦 Packaging:	10 Tablets per Strip
🧪 Strength:	200 mg
🚚 Delivery Time:	6–15 days

🌿 What is Carbamazepine 200 mg (Zeptol)?

Zeptol 200 mg provides an effective maintenance dose of Carbamazepine, a sodium channel blocker that stabilizes hyperexcitable neuronal membranes and reduces repetitive neuronal firing. This dosage is commonly used in chronic management and dose titration schedules for seizure control.

Clinical studies show that starting at 200 mg twice daily achieves therapeutic plasma concentrations suitable for many patients, with reductions in seizure frequency and relief from trigeminal neuralgia pain.

For prescribing details and safety guidance, refer to the FDA label for Tegretol and the Drugs.com monograph. Additional resources include the NHS Medicines A–Z entry and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C15H12N2O
Molecular Weight	236.27 g/mol
Bioavailability	~75%
Metabolism	Hepatic (CYP3A4)
Half-Life	12–17 hours

Carbamazepine’s primary mechanism is inhibition of voltage-gated sodium channels, dampening neuronal hyperexcitability.

💡 Indications & Dosing

Condition	Dose & Administration
Partial & Generalized Tonic-Clonic Seizures	200 mg twice daily; titrate weekly by 200–400 mg to target 800–1,200 mg/day
Trigeminal Neuralgia	100 mg twice daily; increase to 200 mg twice daily based on response

Administer with meals to minimize gastrointestinal upset. Therapeutic drug monitoring is advised.

⚠️ Warnings & Side Effects

Common:

Drowsiness, dizziness
Nausea, blurred vision
Hyponatremia

Serious:

Hypersensitivity reactions (SJS/TEN) in HLA-B*1502 carriers
Hematologic abnormalities (aplastic anemia, agranulocytosis)
Liver toxicity

Screen at-risk patients for HLA-B*1502. Monitor blood counts, liver enzymes, sodium levels, and report rashes immediately.

🏥 Storage Instructions

Store Zeptol 200 mg at 20–25°C in original packaging. Protect from moisture and direct sunlight.

🌐 Availability & Purchasing

USA: Prescription-only; carbamazepine generics available.
UK & EU: Prescription required; widely available.
Australia: Prescription and TGA approval for import.

Import from India may reduce costs; ensure regulatory compliance and valid prescription.

🔗 Related Antiepileptic Drugs

Zeptol CR 400 mg – extended-release formulation of carbamazepine.
Levetiracetam 500 mg – adjunctive AED.

🎥 Educational Video on Carbamazepine

👩‍⚕️ Expert Insight: Dr. Neeta Sharma, Neurologist

“A 200 mg twice-daily regimen provides stable plasma levels for many patients. Regular monitoring for genetic susceptibility and blood parameters optimizes safety.”