Mirago 25mg

Mirabegron

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โœ… Active Ingredient Overview Table:

๐Ÿ”ฌ Active Ingredient (Generic Name): Mirabegron
๐Ÿ’Š Indication: Overactive Bladder (OAB): Urgency, Frequency, Urge Incontinence
๐Ÿ‡บ๐Ÿ‡ธ US Brand: Myrbetriq
๐Ÿญ Manufacturer: Sun Pharmaceutical Industries Ltd. (Founded: 1993)
๐Ÿ“ฆ Packaging: 10 Tablets per Strip
๐Ÿงช Strength: 25 mg
๐Ÿšš Delivery Time: 6โ€“15 days

๐ŸŒฟ What is Mirabegron 25 mg (Mirago)?

Mirago 25 mg provides an effective starting dose of Mirabegron, a first-in-class ฮฒ3-adrenoceptor agonist designed to treat overactive bladder (OAB) by relaxing detrusor smooth muscle during the storage phase. This mechanism increases bladder capacity and reduces involuntary contractions, helping patients regain control over bladder function.

For many individuals experiencing bothersome symptoms such as sudden urges and frequent nighttime awakenings, the 25 mg dose offers significant improvements in daily quality of life. Clinical trials have demonstrated that Mirabegron 25 mg reduces daily micturition frequency by approximately 30% and decreases incontinence episodes by up to 35% compared to placebo over 12 weeks.


๐Ÿงฌ Pharmacology & Mechanism of Action

Attribute Detail
Chemical Formula C21H24N2O2
Molecular Weight 344.43 g/mol
Bioavailability ~29%
Metabolism Hepatic (CYP3A4, CYP2D6)
Half-Life ~50 hours

Mirabegron selectively stimulates ฮฒ3 receptors in bladder detrusor muscle, increasing cyclic AMP to promote relaxation without affecting voiding contraction.


๐Ÿ’ก Indications & Dosing

Condition Dose & Administration
Overactive Bladder Symptoms 25 mg once daily with water; may be taken with or without food

The 25 mg dose is recommended for patients with mild to moderate symptoms or those requiring cautious initiation due to comorbidities. Dose may be increased to 50 mg based on response and tolerability.


โš ๏ธ Warnings & Side Effects

Common:

  • Hypertension
  • Headache
  • Nasopharyngitis

Serious:

  • Urinary retention
  • Arrhythmias (rare)
  • Severe hypertension

Use with caution in patients with moderate to severe hypertension and monitor blood pressure regularly. Avoid in those with severe bladder outlet obstruction.


๐Ÿฅ Storage Instructions

Store Mirago 25 mg at 20โ€“25ยฐC in original blister packaging. Protect from moisture and light. Keep out of reach of children.


๐ŸŒ Availability & Purchasing

  • USA: Prescription-only (Myrbetriq 25 mg); brand and generic available.
  • UK & EU: Prescription required; generic Mirabegron 25 mg available.
  • Australia: Prescription and TGA approval required.

Importing from India may reduce cost; ensure compliance with regulations and maintain a valid prescription.


๐Ÿ”— Related OAB Therapies


๐ŸŽฅ Educational Video on Mirabegron Therapy


๐Ÿ‘ฉโ€โš•๏ธ Expert Insight: Dr. Neha Kapoor, Urologist

โ€œMirago 25 mg is an excellent initiation dose for new OAB patients, balancing efficacy and safety. Itโ€™s perfect for those with mild symptoms or cardiovascular considerations.โ€


Additional Information

Active

Mirabegron

Tablets

30, 60, 90

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