✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Ketoprofen 2.5%
💊 Indication:	Relief of Pain and Inflammation in Musculoskeletal Disorders: Sprains, Strains, Bursitis, Tendinitis
🇺🇸 US Brand:	Ketofen Gel
🏭 Manufacturer:	Menarini India Pvt Ltd (Founded: 1978)
📦 Packaging:	30 g Tube
🧪 Strength:	2.5% (25 mg/g) Ketoprofen
🚚 Delivery Time:	6–15 days

🌿 What is Ketoprofen 2.5% Gel (Fastum Gel)?

Fastum Gel contains Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) formulated for topical use at 2.5% concentration. It provides targeted relief of acute pain and inflammation in soft tissues. Fastum Gel reduces prostaglandin synthesis by inhibiting COX-1 and COX-2 enzymes locally, minimizing systemic exposure.

For comprehensive prescribing and safety information, see the FDA topical ketoprofen guidance, the Drugs.com topical NSAIDs guide, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C16H14O3
Molecular Weight	254.28 g/mol
Permeation	Enhanced transdermal absorption with gel base
Metabolism	Minimal systemic absorption; hepatic if absorbed
Duration of Effect	Up to 8 hours per application

Ketoprofen’s local COX inhibition attenuates inflammatory mediators in affected tissues, alleviating pain and reducing swelling.

💡 Indications & Application

Sprains & Strains: Apply a thin layer to the affected area 3–4 times daily and massage gently.
Bursitis & Tendinitis: Use as needed for symptom relief; avoid occlusive dressings.
Arthralgia & Myalgia: Continue use for up to 14 days; if symptoms persist, seek medical advice.

Wash hands before and after use. Avoid contact with eyes, mucous membranes, and open wounds.

⚠️ Warnings & Side Effects

Common (Local):

Skin irritation, redness
Pruritus, burning sensation

Serious (Rare):

Contact dermatitis
Photosensitivity reactions

Do not apply to broken or eczematous skin. Discontinue if severe skin reaction occurs. Avoid sun exposure to treated area.

🏥 Storage Instructions

Store Fastum Gel at 20–25°C. Protect from freezing and direct sunlight. Keep tube tightly closed and out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only topical NSAID; limited availability.
UK & EU: Prescription required; topical ketoprofen available in various formulations.
Australia: Prescription and TGA approval required.

International import may lower costs; ensure compliance with local regulations and maintain a valid prescription.

🎥 Educational Video on Topical NSAIDs

👩‍⚕️ Expert Insight: Dr. Anita Sharma, Pain Specialist

“Fastum Gel offers efficient local control of inflammation and pain in acute soft tissue injuries, reducing reliance on oral NSAIDs and their systemic risks.”