✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Ketoprofen 100 mg
💊 Indication:	Relief of Acute and Chronic Musculoskeletal Pain (Sprains, Strains, Osteoarthritis)
🇺🇸 US Brand:	Flector Patch (Diclofenac) – analogous topical patch concept
🏭 Manufacturer:	Zuventus Healthcare (Founded: 1991)
📦 Packaging:	7 Transdermal Patches per Packet
🧪 Strength:	30 mg per patch (Ketoprofen)
🚚 Delivery Time:	6–15 days

🌿 What is Ketoprofen 100 mg Transdermal Patch (Ketoplast Plus)?

Ketoplast Plus delivers 100 mg of Ketoprofen per patch through the skin, providing sustained, localized NSAID therapy directly to affected tissues. It inhibits COX-1 and COX-2 enzymes in underlying muscles and joints, reducing inflammation and pain without significant systemic exposure.

For detailed prescribing information, safety profiles, and application guidelines, consult the Drugs.com monograph on topical ketoprofen, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C16H14O3
Molecular Weight	254.28 g/mol
Permeation	Enhanced transdermal diffusion via matrix patch
Metabolism	Minimal systemic absorption; hepatic if absorbed
Duration of Effect	Continuous delivery over 24 hours

Ketoprofen blocks prostaglandin synthesis locally, attenuating inflammatory mediators and providing sustained analgesia.

💡 Indications & Application

Sprains & Strains: Apply one patch to intact skin over the painful area once daily.
Osteoarthritis: Use patches on large joint surfaces, replace every 24 hours.
Chronic Musculoskeletal Pain: Patches can be applied consecutively for up to 7 days; monitor skin condition.

Do not apply to broken or inflamed skin. Rotate patch sites to minimize skin irritation.

⚠️ Warnings & Side Effects

Common (Local):

Skin irritation, erythema
Itching, burning sensation

Serious (Rare):

Contact dermatitis
Photosensitivity reactions

Discontinue if severe dermatitis occurs. Avoid exposure to sunlight on applied area. Do not use occlusive dressings.

🏥 Storage Instructions

Store Ketoplast Plus patches at 20–25°C. Protect from moisture and direct sunlight. Keep in sealed packet until use.

🌐 Availability & Purchasing

USA: Topical ketoprofen patches not available; diclofenac patch Flector as alternative.
UK & EU: Some markets offer ketoprofen patches by prescription.
Australia: Prescription topical patches available; check TGA approval.

International import may reduce costs; ensure regulatory compliance and hold valid prescription.

🔗 Related Topical and Transdermal Analgesics

Fastum Gel 2.5% – ketoprofen topical gel.

🎥 Educational Video on Transdermal NSAID Therapy

👩‍⚕️ Expert Insight: Dr. Rakesh Jain, Rheumatologist

“Ketoplast Plus patches offer continuous, targeted NSAID delivery without peaks and troughs of oral dosing. They’re especially useful in chronic joint pain and acute injuries when systemic NSAIDs pose risks.”