✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Diclofenac Sodium
💊 Indication:	Relief of Pain and Inflammation in Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
🇺🇸 US Brand:	Voltaren® SR
🏭 Manufacturer:	Novartis India Ltd (Founded: 1997)
📦 Packaging:	15 Extended-Release Tablets per Strip
🧪 Strength:	100 mg SR
🚚 Delivery Time:	6–15 days

🌿 What is Diclofenac 100 mg SR (Voveran SR)?

Voveran SR provides 100 mg of diclofenac sodium in an extended-release formulation, delivering sustained anti-inflammatory and analgesic effects over 24 hours. Diclofenac inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis, pain, and swelling in chronic inflammatory conditions.

For full prescribing and safety information, consult the FDA label for Voltaren SR, the Drugs.com monograph, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C14H11Cl2NO2
Molecular Weight	296.15 g/mol
Bioavailability	~50% (SR)
Metabolism	Hepatic (CYP2C9)
Half-Life	~12 hours (SR)

Diclofenac’s sustained COX inhibition modulates inflammatory cascades, providing prolonged relief with once-daily dosing.

💡 Indications & Dosing

Condition	Dose & Administration
Osteoarthritis, Rheumatoid Arthritis	100 mg SR once daily with food to reduce GI irritation
Ankylosing Spondylitis	100 mg SR once daily; may split into 50 mg twice daily if needed

Swallow whole; do not crush or chew. Monitor for GI tolerance and adjust dose if required.

⚠️ Warnings & Side Effects

Common:

GI upset, dyspepsia
Headache, dizziness
Elevated liver enzymes

Serious:

GI bleeding, ulceration
Cardiovascular thrombotic events (MI, stroke)
Hepatotoxicity, renal impairment

Contraindicated in active GI bleeding, severe heart failure, and NSAID hypersensitivity. Use lowest effective dose for shortest duration; monitor renal, hepatic, and cardiovascular status.

🏥 Storage Instructions

Store Voveran SR at 20–25°C in original blister. Protect from moisture and light. Keep out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only SR diclofenac available as Voltaren® SR.
UK & EU: Prescription required; generic SR formulations accessible.
Australia: Prescription and TGA approval required.

Importing from India may reduce costs; ensure regulatory compliance and valid prescription.

🔗 Related NSAID Options

Celecoxib 100 mg – COX-2 selective.
Meloxicam 15 mg – preferential COX-2.
Ibuprofen 600 mg – extended-release NSAID.

🎥 Educational Video on Diclofenac SR

👨‍⚕️ Expert Insight: Dr. Rajat Verma, Rheumatologist

“Voveran SR 100 mg offers consistent 24-hour symptom control for chronic arthritis patients, improving adherence and minimizing nighttime flare-ups when taken once daily in the evening.”