✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Permethrin
💊 Indication:	Scabies (Sarcoptes scabiei infestation)
🇺🇸 US Brand:	Elimite, Nix
🏭 Manufacturer:	Healing Pharma (Founded: 2010)
📦 Packaging:	30 g Tube
🧪 Strength:	5% w/w
🚚 Delivery Time:	6–15 days

🌿 What is Permethrin 5% Cream (Permiforce)?

Permiforce Cream contains 5% permethrin, a potent synthetic pyrethroid that acts on the nervous system of mites. It induces sustained paralysis of Sarcoptes scabiei, thereby eradicating all life stages of the parasite. Applied topically, Permiforce Cream penetrates the stratum corneum and remains active for 24 hours, ensuring complete scabicidal activity in a single application.

Scabies causes intense pruritus and characteristic burrows; left untreated, secondary infections and widespread rash can occur. Permethrin 5% is the first-line therapy recommended by dermatology guidelines due to its high efficacy (>90% cure rates) and favorable safety profile.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C21H20Cl2O3
Molecular Weight	391.29 g/mol
Mode of Action	Voltage-gated sodium channel disruption
Residual Activity	Up to 24 hours

Permethrin binds parasitic sodium channels, causing prolonged depolarization, paralysis, and death of mites and their eggs.

💡 Indications & Application

Condition	Application Protocol
Scabies Infestation	Apply cream from head to soles, leave for 8–14 hours, then rinse. Single application needed; repeat in 1 week if live mites detected.

Apply to clean, dry skin, covering all body areas including under nails. Wash bedding and clothing in hot water.

⚠️ Warnings & Side Effects

Common:

Mild burning or stinging
Itching, redness at application site

Serious (rare):

Allergic contact dermatitis
Neurotoxicity if over-applied (avoid mucous membranes)

Avoid application to broken skin or eyes. In case of contact, rinse thoroughly with water. Use with caution in infants (<2 months) and pregnant women.

🏥 Storage Instructions

Store Permiforce Cream at 20–25°C in its original tube. Protect from light and extreme temperatures. Keep out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only (Elimite). OTC 1% permethrin for lice.
UK & EU: Prescription required; generic permethrin creams available.
Australia: Prescription and TGA approval needed.

Permiforce provides an affordable alternative. Ensure compliance with local regulations and consult healthcare providers for guidance.

🔗 Related Parasitic Treatments

Ivermectin 6 mg Tablets – systemic therapy.

🎥 Educational Video on Scabies Management

👩‍⚕️ Expert Insight: Dr. Arjun Mehta, Dermatologist

“Permethrin 5% cream is the gold standard for scabies treatment. A single overnight application cures most cases; patient education on application technique and hygiene is crucial to prevent reinfestation.”