✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Cefdinir
💊 Indication:	Bacterial Infections (Respiratory, Skin, Urinary)
🇺🇸 US Brand Equivalent:	Omnicef
🏭 Manufacturer:	Unichem Laboratories Ltd (Founded: 1944)
📦 Packaging:	10 Capsules per Strip
🧪 Strength:	300 mg
🚚 Delivery Time:	6–15 days

🌿 What is Cefdinir 300 mg (Sefdin)?

Sefdin contains Cefdinir, a third-generation oral cephalosporin antibiotic. It is indicated for treating a variety of bacterial infections including community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, acute bacterial sinusitis, pharyngitis/tonsillitis, uncomplicated skin and skin structure infections, and uncomplicated urinary tract infections. Cefdinir works by inhibiting bacterial cell wall synthesis, leading to cell lysis and bacterial death. Its broad-spectrum activity covers many Gram-positive and Gram-negative organisms.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C14H13N5O5S·*
Molecular Weight	395.43 g/mol
Mechanism of Action	Binds to penicillin-binding proteins (PBPs) → inhibits transpeptidation step in peptidoglycan synthesis → weakens cell wall → bactericidal
Bioavailability	~63%
Half-Life	~1.7 hours
Metabolism & Excretion	Minimally metabolized; excreted primarily unchanged via urine

*Empirical formula indicates active moiety. Numbers rounded for readability.

💡 Indications & Usage

Condition	Recommended Course
Community-Acquired Pneumonia (CAP)	300 mg every 12 hours for 5–10 days
Acute Bacterial Bronchitis Exacerbation	300 mg every 12 hours for 5–10 days
Acute Bacterial Sinusitis (ABRS)	300 mg every 12 hours for 10 days
Pharyngitis/Tonsillitis	300 mg every 12 hours for 10 days
Uncomplicated Skin & Skin Structure Infections	300 mg every 12 hours for 5–10 days
Uncomplicated Urinary Tract Infections (UTI)	300 mg every 12 hours for 3 days

Administration: Swallow capsule whole with water; may take with or without food.
Missed Dose: If a dose is missed, take as soon as remembered unless next dose is imminent; do not double dose.
Complete Course: Finish the entire prescribed course even if symptoms improve earlier to prevent resistance.

⚠️ Warnings & Side Effects

Common Side Effects:

Diarrhea or loose stools
Nausea
Headache
Abdominal pain

Less Common:

Rash or urticaria
Vaginal candidiasis (thrush)
Transient elevations in liver enzymes

Serious (Rare):

Clostridioides difficile-associated diarrhea (CDAD)
Anaphylaxis or severe hypersensitivity reactions
Stevens-Johnson Syndrome or toxic epidermal necrolysis (very rare)

Precautions:

History of Allergies: Contraindicated in patients with known cephalosporin or penicillin allergy.
C. difficile Risk: Prolonged or repeated therapy may lead to overgrowth of non-susceptible organisms.
Renal Impairment: Dose adjustment required in creatinine clearance <30 mL/min. Reduce to 300 mg once daily.
Pregnancy & Lactation: Use only if clearly needed; minimal excretion into breast milk but monitor nursing infants.
Pediatric Use: Approved for ages 6 months and older; dosage based on weight (14 mg/kg/day divided every 12 hrs, max 300 mg/day).

🏥 Storage Instructions

Store Sefdin Capsules at 20–25°C (68–77°F). Protect from moisture and direct sunlight. Keep in original blister pack until use. Discard 6 months after opening. Keep out of reach of children.

🌐 Availability & Purchasing

United States: Prescription required; sold as Omnicef (Cefdinir) 300 mg capsules/tablets. Generics available.
United Kingdom & EU: Prescription-only; generics attainable after specialist consultation.
Australia: TGA-approved; prescription necessary; available as generic Cefdinir.

Importing Sefdin from India:
Purchasing Sefdin 300 mg from India offers significant cost savings. Ensure a valid prescription, verify regulatory compliance for import, and confirm authenticity to avoid counterfeit products.

🔗 Authoritative Resources

Drugs.com: Cefdinir Monograph

🔗Related Antibiotic Therapies (Indian Brands)

Azithral 500 mg – Azithromycin by Cadila Healthcare for atypical respiratory infections.

🎥 Educational Video on Cefdinir Use & Safety

👨‍⚕️ Expert Insight: Dr. Anil Kapoor, Infectious Disease Specialist

“Cefdinir is an excellent option for outpatient management of common bacterial infections due to its convenient dosing and broad-spectrum coverage. Always counsel patients on finishing the full antibiotic course to prevent resistance.”