📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Active Ingredient	Methylprednisolone Sodium Succinate
🧪 Strength	1000 mg
🏭 Manufacturer	Pfizer India Ltd
💉 Form	Injection (Lyophilized Powder)
📦 Packaging	2 ml in 1 vial
⏱️ Delivery Time	6 to 15 days

🧬 What is Solu-Medrol 1000mg Used For?

Solu-Medrol 1000mg is a high-dose intravenous corticosteroid injection manufactured by Pfizer India Ltd. It contains methylprednisolone sodium succinate, a synthetic glucocorticoid used in severe medical emergencies that require rapid and powerful suppression of the immune system or inflammation.

This ultra-high-dose formulation is critical in managing acute autoimmune crises, including multiple sclerosis relapses, systemic lupus erythematosus (SLE) flare-ups, organ transplant rejection episodes, and acute spinal cord trauma.

Due to its high potency, Solu-Medrol 1000mg is most often administered in intensive care units (ICUs), emergency departments, or specialized neurology and rheumatology clinics. The drug is administered via intravenous infusion and has a rapid onset of action. It is often given in pulse therapy—short, high-dose bursts over several days.

Pfizer India ensures the product meets stringent international manufacturing standards, including WHO-GMP and CDSCO compliance. Patients around the globe rely on Solu-Medrol 1000mg for timely intervention in life-threatening flare-ups.

🎥 Educational Video: High-Dose Solu-Medrol Therapy

📺 “When Every Second Counts – Solu-Medrol 1000mg in Critical Care”

🎬 Video Placeholder – Learn how to reconstitute, dose, and monitor Solu-Medrol 1000mg in urgent clinical settings.

Medical professionals should strictly supervise all administrations.

🩺 Indications

Acute exacerbations of multiple sclerosis
Severe lupus nephritis or systemic lupus flare
Acute rejection in organ transplant patients
Rheumatoid arthritis crisis
Autoimmune vasculitis
Acute spinal cord compression or trauma
Life-threatening anaphylaxis (as part of combination therapy)

💉 Dosage & Administration

🏥 Condition	💉 Suggested Dosage
MS flare-up	1000 mg IV daily for 3–5 days
Lupus nephritis	1000 mg IV for 1–3 days (pulse)
Transplant rejection	500–1000 mg IV per day as needed
Spinal cord injury	Single 1000 mg IV dose (within 8 hrs)

Administration: Reconstitute the vial with sterile water and administer IV slowly over 30–60 minutes. Monitor vital signs and blood glucose closely.

⚠️ Side Effects & Precautions

💥 Frequent Effects	❗ Severe Adverse Effects
Flushed face, dizziness	Adrenal crisis, hyperglycemia, arrhythmia
Fluid retention, weight gain	GI bleeding, infection reactivation
Mood changes, sleep disturbance	Psychosis, avascular necrosis, Cushing’s signs

🧃 Storage & Stability

Store at temperatures below 25°C
Do not freeze the dry powder or solution
Use immediately after reconstitution
Discard any unused portion

🌍 International Availability & Import Guide

🌎 Region	📦 Import Permission	📋 Requirements
🇺🇸 USA	Permitted under FDA guidelines	Requires valid prescription
🇬🇧 UK	Allowed via MHRA import scheme	Licensed prescription needed
🇦🇺 Australia	Available under TGA exemptions	Requires prescription/doctor note

🔗 Related Corticosteroid Products (Internal Links)

💊 Product Name	🏭 Manufacturer	📖 Brief Description
Depo-Medrol Injection	Pfizer India	Long-acting methylprednisolone acetate for chronic inflammation via IM use.
Predmet Injection	Sun Pharma	Fast-acting corticosteroid for arthritis, allergic reactions, and flares.
Defcort Tablets	Glenmark Pharmaceuticals	Deflazacort-based oral steroid used for chronic inflammatory disease management.
Wysolone Tablets	Pfizer India	Oral prednisolone for routine corticosteroid therapy in autoimmune diseases.
Omnacortil Oral Tablets	Macleods Pharmaceuticals	Widely used prednisolone brand for systemic inflammatory control.

📚 References & External Sources

🩺 Expert Commentary – Dr. Neha Kulkarni, MD Neurology

“When facing neurological or autoimmune emergencies, Solu-Medrol 1000mg is a gold standard for rapid immune modulation. Its speed of action and hospital-ready formulation make it a dependable choice across specialties.”

⚠️ Disclaimer

This article is intended for informational purposes only. Solu-Medrol 1000mg must be administered by a healthcare provider. Importation must comply with local regulatory laws.