📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Active Ingredient	Clomiphene Citrate 100 mg
🧪 Formulation	Selective Estrogen Receptor Modulator (SERM)
🏭 Manufacturer	Serum Institute of India
💊 Dosage Form	Oral Tablet
📦 Packaging	5 Tablets in 1 Strip
🩺 Indication	Female infertility, PCOS-related ovulatory failure
🇺🇸 US Brand Equivalent	Clomid
⏱️ Delivery Time	6 to 15 days

🧬 Introduction – What is Siphene 100mg (Clomiphene)?

Siphene 100mg, manufactured by Serum Institute of India, is a high-strength oral fertility medication that contains Clomiphene Citrate, a well-established Selective Estrogen Receptor Modulator (SERM). This 100mg dose is typically prescribed when lower dosages (25mg or 50mg) have failed to induce ovulation, making it an important step in step-up ovulation induction protocols.

This dosage is frequently used in women with resistant PCOS, hypothalamic anovulation, or those undergoing advanced fertility procedures like intrauterine insemination (IUI) or in-vitro fertilization (IVF). By increasing gonadotropin levels such as FSH (follicle-stimulating hormone) and LH (luteinizing hormone), Clomiphene 100mg helps mature ovarian follicles, improving the chances of ovulation and successful conception.

The higher dose requires careful monitoring to avoid Ovarian Hyperstimulation Syndrome (OHSS) and multiple pregnancies, but its efficacy is widely supported by clinical studies. Siphene is considered a reliable, cost-effective, and globally available option for individuals struggling with infertility, particularly in resource-limited settings.

🎥 Video Overview – Understanding Siphene 100mg in Infertility Therapy

📺 “Clomiphene 100mg: High-Dose Ovulation Induction Explained“

🎬 Video Placeholder – Covers usage strategy, hormonal mechanism, ultrasound monitoring, and success rates.

Always follow up with hormonal blood work and pelvic ultrasounds when using high-dose Clomiphene.

🔬 Pharmacological Profile

🧪 Parameter	📊 Details
Drug Class	Selective Estrogen Receptor Modulator (SERM)
Mechanism	Inhibits estrogen receptors in hypothalamus
Target Hormones	Increases secretion of FSH & LH
Ovulation Onset	5–10 days after last tablet
Half-Life	~5–7 days
Standard Course	5 consecutive days per menstrual cycle

💊 Dosage & Administration

📅 Cycle Days	💊 Dosage	📌 Clinical Notes
Day 2 to Day 6	100mg once daily	Preferred for Clomiphene-resistant ovulatory dysfunction
Day 3 to Day 7	100mg once daily	May be recommended by doctor depending on cycle protocol

Monitoring via ultrasound and serum hormone levels is essential.

⚠️ Side Effects & Risks

💥 Common Side Effects	❗ Serious Risks (Use With Caution)
Hot flashes, bloating	Ovarian Hyperstimulation Syndrome (OHSS)
Headache, dizziness	Enlarged ovaries, visual disturbances
Nausea, breast discomfort	Multiple follicle development

Do Not Use If You:

are already pregnant
have active liver disease
have ovarian cysts unrelated to PCOS

🧃 Storage Guidelines

Store at room temperature below 25°C
Keep in a dry place, away from light and moisture
Do not use expired medication

🌍 Global Availability – How to Buy Siphene 100mg Internationally

🌎 Country	📦 Import Allowed?	📋 Prescription Required
🇺🇸 USA	Yes – via FDA personal import	✅ Yes
🇬🇧 UK	Yes – under MHRA guidelines	✅ Yes
🇦🇺 Australia	Yes – under TGA import scheme	✅ Yes

🔗 Related Ovulation Medications

💊 Product	🏭 Manufacturer	📖 Description
Clomiford 100mg	Healing Pharma	High-dose Clomiphene for resistant ovulatory cases
Fertomid 100mg	Cipla Ltd.	Widely prescribed for Clomiphene-resistant patients
Clomid 100mg	Sanofi Aventis	Original high-dose US brand of Clomiphene
Letoval 5mg	Sun Pharma	Letrozole for patients unresponsive to Clomiphene
Ovulet 100mg	Intas Pharmaceuticals	Another high-dose clomiphene citrate option

📚 Trusted Medical References

🩺 Clinical Review – Dr. Rhea Mehta, MD (Gynecologist & Fertility Specialist)

“Siphene 100mg is often used as a secondary escalation for women who do not respond to lower doses of Clomiphene. Its efficacy is proven, but careful monitoring is vital to ensure optimal and safe ovulation outcomes.”

⚠️ Disclaimer

This article is for informational purposes only. Do not self-medicate. Always consult a certified fertility specialist before using Siphene 100mg or any Clomiphene-containing medication.