| ๐ท๏ธย Parameter | ๐ย Details |
|---|---|
| ๐งฌ Active Ingredient | Trihexyphenidyl Hydrochloride |
| ๐ Indication | Parkinsonism, Drug-Induced Extrapyramidal Symptoms (EPS), Dystonia |
| ๐บ๐ธ US Brand | Artaneยฎ (discontinued); generic available |
| ๐ญ Manufacturer | Intas Pharmaceuticals Ltd. |
| ๐ฆ Packaging | Blister strips of 10 tablets |
| ๐ช Strength | 2 mg |
| ๐ Delivery Time | 7โ15 days (Worldwide) |
๐ง Introduction to Bexol (Trihexyphenidyl)
Bexol containsย Trihexyphenidyl, a central anticholinergic agent manufactured by Intas India. It restores dopamine-acetylcholine balance in basal ganglia, providing relief for:
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๐ฅผย Parkinson’s symptoms: Rigidity, tremors, and sialorrhea (excessive drooling)
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๐ย Drug-induced EPS: Caused by antipsychotics (e.g., rigidity from Haloperidol)
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๐ชย Dystonia: Muscle spasms in neck/limbs (off-label)
Unlike levodopa, Bexol doesn’t cause dyskinesias but requires cautious dosing in elderly due to cognitive side effects.
๐ Dosage & Indications
| ๐ย Indication | ๐งชย Dosage | โฑ๏ธย Frequency | ๐กย Route |
|---|---|---|---|
| Parkinsonism (Adults) | 1โ2 mg/day โ Max 15 mg/day | 3โ4 divided doses | Oral |
| Drug-Induced EPS (Adults) | 5โ15 mg/day | Divided doses | Oral |
| Dystonia (Off-label) | 2โ5 mg TID | Max 20 mg/day | Oral |
| Pediatric EPS (โฅ3 years) | 0.05โ0.1 mg/kg/day | Divided doses | Oral |
โ ๏ธ Side Effects, Storage & Warnings
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โ Common Side Effects: Dry mouth, blurred vision, constipation, urinary retention.
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๐ซ Serious Effects:
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Confusion/hallucinations (elderly)
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Angle-closure glaucoma (emergency)
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Tachycardia (heart rate >100 bpm)
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โ๏ธ Storage: Below 30ยฐC; protect from moisture (desiccant in bottle).
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โ ๏ธ Warnings:
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Contraindicated in glaucoma, myasthenia gravis, or bowel obstruction.
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Avoid in dementia patients (โ cognitive impairment risk).
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Discontinue gradually to prevent rebound symptoms.
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๐ Global Availability & Shipping
| ๐ย Region | ๐ฆย Shipping | ๐ตย Price (10 tablets) | ๐ย Prescription |
|---|---|---|---|
| ๐บ๐ธ USA | โ Yes | $15โ$25 | Required |
| ๐ฌ๐ง UK | โ Yes | ยฃ12โยฃ20 | Required |
| ๐ฆ๐บ Australia | โ Yes | AUD 20โ35 | Required |
๐ Related Indian Alternatives (Different in Same Category)
| ๐ Product Name | ๐ญ Manufacturer | ๐ Internal Link |
|---|---|---|
| Pacitane (Trihexyphenidyl) | Sun Pharma | Pacitane |
| Artane (Trihexyphenidyl) | Pfizer | Artane |
| Syndopa (Levodopa-Carbidopa) | Sun Pharma | Syndopa |
| Pramipex (Pramipexole) | Intas | Pramipex |
| Ropark (Ropinirole) | Sun Pharma | Ropark |
| Benexol (Benztropine) | Alembic Pharma | Benexol |
๐ External Medical References
๐ฉบ Expert Commentary
Dr. Vikram Patel, Neurologist:
*”Bexol remains essential for young Parkinson’s patients with tremor-predominant symptoms. For antipsychotic-induced EPS, start with 2mg BID and monitor for anticholinergic toxicity. Rotigotine patches ([Neupro]) are preferable for elderly.”*
๐ Disclaimer
This article is informational only. Consult a neurologist before use. Intas’ Bexol is not FDA-approved for dystonia.
๐ก Clinical Tips:
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Acute Dystonia Rescue: 5 mg IM + posture correction (onset: 10โ15 min).
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Dry Mouth Management: Sugar-free gum/pilocarpine drops.
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Switching Strategy: Replace 5 mg Bexol with 2 mg [Benexol] (less cognitive impact).




