✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Azithromycin
💊 Indication:	Bacterial Infections (Respiratory, Skin, STIs, Otitis Media, Pharyngitis)
🇺🇸 US Brand Equivalent:	Zithromax
🏭 Manufacturer:	Cipla Limited (Founded: 1935)
📦 Packaging:	250 mg: 6 Tablet per Strip; 500 mg: 3 Tablets per Strip; 1000 mg: 1 Tablets per Strip
🧪 Strengths:	250 mg, 500 mg, 1000 mg
🚚 Delivery Time:	6–15 days

🌿 What is Azithromycin (Azee)?

Azee contains Azithromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It provides broad-spectrum coverage against Gram-positive and Gram-negative organisms, including atypical pathogens (Mycoplasma, Chlamydia, Legionella). Awee’s once-daily dosing and tissue penetration make it suitable for respiratory tract infections, skin and soft tissue infections, sexually transmitted infections, and community-acquired pneumonia.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C38H72N2O12
Molecular Weight	748.98 g/mol
Mechanism of Action	Binds to the 23S rRNA of the 50S ribosomal subunit → blocks translocation → inhibits protein synthesis → bacteriostatic at low concentrations, bactericidal at high concentrations.
Bioavailability	~37% (oral)
Half-Life	~68 hours
Metabolism & Excretion	Minimally hepatic metabolism; excreted primarily unchanged in bile; small fraction in urine.

💡 Indications & Dosing Regimens

Condition	Dose & Duration
Community-Acquired Pneumonia (Adults)	• 500 mg once daily for 3 days; or 500 mg on Day 1, then 250 mg once daily on Days 2–5.
Acute Bacterial Sinusitis	• 500 mg once daily for 3 days.
Pharyngitis/Tonsillitis (Streptococcal)	• 500 mg once on Day 1, then 250 mg once daily on Days 2–5.
Uncomplicated Skin & Soft Tissue Infections	• 500 mg once daily for 5 days.
Chlamydia trachomatis Infections (STI)	• 1000 mg as single dose (two 500 mg tablets taken together).
Otitis Media (Children):	• 10 mg/kg once daily for 3 days (max 500 mg/day).

Administration: Swallow tablets whole with water, with or without food.
Missed Dose: If a dose is missed, take as soon as remembered unless it is close to the next scheduled dose; do not double dose.
Complete Course: Finish the entire course even if symptoms improve early to prevent resistance.

⚠️ Warnings & Side Effects

Common Side Effects (≥1%):

Gastrointestinal: Diarrhea, nausea, abdominal pain, vomiting
Headache

Less Common:

Transient elevated liver enzymes (AST/ALT)
Dizziness, fatigue

Serious (Rare):

QT prolongation → risk arrhythmias (torsades de pointes)
Hepatotoxicity (cholestatic hepatitis)
Clostridioides difficile–associated diarrhea (CDAD)
Severe hypersensitivity (anaphylaxis, angioedema)

Precautions:

Cardiac Risk: Contraindicated in patients with known QT prolongation or on other QT‑prolonging drugs.
Hepatic Impairment: Use with caution; monitor liver function.
Pediatric Use: Approved for children ≥6 months, weight-based dosing required.
Pregnancy & Lactation: Category B; use only if clearly needed; minimal excretion into breast milk.

🩺 Storage Guidelines

Store Azee tablets at 20–25°C (68–77°F). Protect from moisture and excessive heat. Keep tablets in original strip until use. Discard expired medications. Keep out of reach of children.

🌐 Availability & Purchasing

United States: Prescription required; available as Zithromax (250 mg, 500 mg, 600 mg).
United Kingdom: Prescription-only; generic azithromycin formulations available.
Australia: TGA-approved; prescription necessary; available as generics.

Importing Azee from India:
Purchasing Azee from India offers cost savings. Ensure compliance with local import regulations, maintain a valid prescription, and verify product authenticity to avoid counterfeit products.

🔗 Internal Links to Authoritative Resources

🔗 Related Antibiotic Therapies (Indian Brands)

Megaclin 500 mg – Azithromycin 500 mg (alternative brand).

🎥 Educational Video on Azithromycin Use & Safety

👨‍⚕️ Expert Insight: Dr. Priya Kapoor, Infectious Disease Specialist

“Azithromycin’s extended half-life and tissue concentration allow for shorter, more convenient dosing regimens. Its broad coverage makes it a staple in treating community-acquired infections, but clinicians must monitor for QT prolongation in at‑risk patients.”