Name: Aspadol 100 mg
SKU: 22915
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Tapentadol Hydrochloride
💊 Indication:	Moderate to Severe Acute Pain
🇺🇸 US Brand:	Nucynta
🏭 Manufacturer:	Signature Pharma (India) (Founded: 2012)
📦 Packaging:	10 Tablets per Strip
🧪 Strength:	100 mg
🚚 Delivery Time:	6–15 days

🌿 What is Tapentadol 100 mg (Aspadol)?

Aspadol contains Tapentadol, a centrally acting analgesic combining μ-opioid receptor agonism with norepinephrine reuptake inhibition, providing potent relief of moderate to severe acute pain. The dual mechanism enhances analgesia and may reduce typical opioid side effects.

For detailed prescribing guidance, contraindications, and safety data, see the FDA label for Nucynta, the Drugs.com monograph, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C14H23NO2
Molecular Weight	241.34 g/mol
Bioavailability	~32% (oral)
Metabolism	Hepatic (Phase 2 glucuronidation)
Half-Life	~4 hours

Tapentadol’s action at μ-opioid receptors and inhibition of norepinephrine reuptake modulates ascending pain pathways, offering effective analgesia with a potentially lower risk of GI side effects.

💡 Indications & Dosing

Condition	Dose & Administration
Acute Moderate to Severe Pain	50–100 mg every 4–6 hours as needed; max 600 mg/day

Administer with or without food. Adjust dose for elderly or renally impaired patients.

⚠️ Warnings & Side Effects

Common:

Nausea, dizziness
Somnolence
Constipation

Serious:

Respiratory depression
Seizures (in predisposed)
Serotonin syndrome (with SSRIs)

Contraindicated in patients with significant respiratory depression, acute or severe bronchial asthma, or MAOI use within 14 days. Monitor for signs of abuse, addiction, and overdose.

🏥 Storage Instructions

Store Aspadol 100 mg at 20–25°C in original blister pack. Protect from moisture and light. Keep out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only (Nucynta); ER formulation.
UK & EU: Prescription required; tapentadol available as Nucynta.
Australia: Prescription and TGA approval required.

Importing from India may reduce costs; ensure legal compliance and possess valid prescription.

🔗 Related Analgesic Options

Paracetamol 500 mg – non-opioid analgesic.

🎥 Educational Video on Tapentadol

👩‍⚕️ Expert Insight: Dr. Rahul Mehta, Pain Specialist

“Tapentadol offers a novel analgesic profile by combining opioid and noradrenergic mechanisms, providing potent pain relief with a potentially improved tolerability profile compared to traditional opioids.”