Azee

Azithromycin

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โœ… Active Ingredient Overview Table:

๐Ÿ”ฌ Active Ingredient (Generic Name): Azithromycin
๐Ÿ’Š Indication: Bacterial Infections (Respiratory, Skin, STIs, Otitis Media, Pharyngitis)
๐Ÿ‡บ๐Ÿ‡ธ US Brand Equivalent: Zithromax
๐Ÿญ Manufacturer: Cipla Limited (Founded: 1935)
๐Ÿ“ฆ Packaging: 250 mg: 6 Tablet per Strip; 500 mg: 3 Tablets per Strip; 1000 mg: 1 Tablets per Strip
๐Ÿงช Strengths: 250 mg, 500 mg, 1000 mg
๐Ÿšš Delivery Time: 6โ€“15 days

๐ŸŒฟ What is Azithromycin (Azee)?

Azee contains Azithromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It provides broad-spectrum coverage against Gram-positive and Gram-negative organisms, including atypical pathogens (Mycoplasma, Chlamydia, Legionella). Aweeโ€™s once-daily dosing and tissue penetration make it suitable for respiratory tract infections, skin and soft tissue infections, sexually transmitted infections, and community-acquired pneumonia.


๐Ÿงฌ Pharmacology & Mechanism of Action

Attribute Detail
Chemical Formula C38H72N2O12
Molecular Weight 748.98 g/mol
Mechanism of Action Binds to the 23S rRNA of the 50S ribosomal subunit โ†’ blocks translocation โ†’ inhibits protein synthesis โ†’ bacteriostatic at low concentrations, bactericidal at high concentrations.
Bioavailability ~37% (oral)
Half-Life ~68 hours
Metabolism & Excretion Minimally hepatic metabolism; excreted primarily unchanged in bile; small fraction in urine.

๐Ÿ’ก Indications & Dosing Regimens

Condition Dose & Duration
Community-Acquired Pneumonia (Adults) โ€ข 500 mg once daily for 3 days; or 500 mg on Day 1, then 250 mg once daily on Days 2โ€“5.
Acute Bacterial Sinusitis โ€ข 500 mg once daily for 3 days.
Pharyngitis/Tonsillitis (Streptococcal) โ€ข 500 mg once on Day 1, then 250 mg once daily on Days 2โ€“5.
Uncomplicated Skin & Soft Tissue Infections โ€ข 500 mg once daily for 5 days.
Chlamydia trachomatis Infections (STI) โ€ข 1000 mg as single dose (two 500 mg tablets taken together).
Otitis Media (Children): โ€ข 10 mg/kg once daily for 3 days (max 500 mg/day).
  • Administration: Swallow tablets whole with water, with or without food.
  • Missed Dose: If a dose is missed, take as soon as remembered unless it is close to the next scheduled dose; do not double dose.
  • Complete Course: Finish the entire course even if symptoms improve early to prevent resistance.

โš ๏ธ Warnings & Side Effects

Common Side Effects (โ‰ฅ1%):

  • Gastrointestinal: Diarrhea, nausea, abdominal pain, vomiting
  • Headache

Less Common:

  • Transient elevated liver enzymes (AST/ALT)
  • Dizziness, fatigue

Serious (Rare):

  • QT prolongation โ†’ risk arrhythmias (torsades de pointes)
  • Hepatotoxicity (cholestatic hepatitis)
  • Clostridioides difficileโ€“associated diarrhea (CDAD)
  • Severe hypersensitivity (anaphylaxis, angioedema)

Precautions:

  • Cardiac Risk: Contraindicated in patients with known QT prolongation or on other QTโ€‘prolonging drugs.
  • Hepatic Impairment: Use with caution; monitor liver function.
  • Pediatric Use: Approved for children โ‰ฅ6 months, weight-based dosing required.
  • Pregnancy & Lactation: Category B; use only if clearly needed; minimal excretion into breast milk.

๐Ÿฉบ Storage Guidelines

Store Azee tablets at 20โ€“25ยฐC (68โ€“77ยฐF). Protect from moisture and excessive heat. Keep tablets in original strip until use. Discard expired medications. Keep out of reach of children.


๐ŸŒ Availability & Purchasing

  • United States: Prescription required; available as Zithromax (250 mg, 500 mg, 600 mg).
  • United Kingdom: Prescription-only; generic azithromycin formulations available.
  • Australia: TGA-approved; prescription necessary; available as generics.

Importing Azee from India:
Purchasing Azee from India offers cost savings. Ensure compliance with local import regulations, maintain a valid prescription, and verify product authenticity to avoid counterfeit products.


๐Ÿ”— Internal Links to Authoritative Resources


๐Ÿ”— Related Antibiotic Therapies (Indian Brands)


๐ŸŽฅ Educational Video on Azithromycin Use & Safety


๐Ÿ‘จโ€โš•๏ธ Expert Insight: Dr. Priya Kapoor, Infectious Disease Specialist

โ€œAzithromycinโ€™s extended half-life and tissue concentration allow for shorter, more convenient dosing regimens. Its broad coverage makes it a staple in treating community-acquired infections, but clinicians must monitor for QT prolongation in atโ€‘risk patients.โ€


Additional Information

active

Tablets

30, 60, 90

Manufacturer

Cipla

Strength

250mg, 500mg, 1000mg

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