Name: Chlorpromazine
SKU: 25976
Availability: InStock

🏷️ Parameter	🔍 Details
🧬 Active Ingredient	Chlorpromazine Hydrochloride
💊 Indication	Schizophrenia, Bipolar Mania, Severe Nausea/Vomiting, Intractable Hiccups
🇺🇸 US Brand	Thorazine® (discontinued in 2020); generic available
🏭 Manufacturer	Sun Pharmaceutical Industries Ltd.
📦 Packaging	Blister strips of 10 tablets (50mg, 100mg)
💪 Strength	50 mg, 100 mg
🚚 Delivery Time	7–14 days (Worldwide)

🧠 Introduction to Chlorpromazine

Chlorpromazine is a first-generation antipsychotic from the phenothiazine class, manufactured by Sun Pharma. It blocks dopamine D2 receptors in the mesolimbic pathway, reducing hallucinations, agitation, and psychotic symptoms. Beyond psychiatry, it’s used off-label for:

🤢 Chemotherapy-induced nausea/vomiting (25–50mg every 4–6h)
😮 Intractable hiccups (25–50mg TID)
🌀 Tetanus-associated muscle spasms (IV administration)

Historically termed “chemical lobotomy” for its sedative effects, it remains vital in low-resource settings due to low cost.

💊 Dosage & Indications

💉 Indication	🧪 Dosage	⏱️ Frequency	💡 Route
Schizophrenia (Adults)	75–300 mg/day	2–4 divided doses	Oral
Bipolar Mania	100–800 mg/day (Max: 2000 mg/day)	Divided doses	Oral
Severe Nausea (Adults)	10–25 mg every 4–6 hours	PRN	Oral/IM
Intractable Hiccups	25–50 mg TID	Max 5 days	Oral
Pediatric Psychosis	0.5 mg/kg every 4–6 hours	Max 40 mg/day (<5y)	Oral

⚠️ Side Effects, Storage & Warnings

❗ Common Side Effects: Sedation, dry mouth, blurred vision, orthostatic hypotension.
🚫 Serious Effects:
- QT prolongation → Torsades de Pointes (ECG monitoring essential)
- Neuroleptic malignant syndrome (NMS)
- Tardive dyskinesia (long-term use)
❄️ Storage: Below 30°C; protect from light (turns pink if degraded).
⚠️ Warnings:
- Contraindicated in coma, severe CVD, or porphyria.
- Avoid in elderly with dementia (↑ mortality risk).
- Dose adjustment in hepatic impairment.

🌍 Global Availability & Shipping

🌎 Region	📦 Shipping	💵 Price (50mg pack)	📜 Prescription
🇺🇸 USA	✅ Yes	$20–$40	Required
🇬🇧 UK	✅ Yes	£15–£30	Required
🇦🇺 Australia	✅ Yes	AUD 25–45	Required

🔗 Related Indian Alternatives (Different in Same Category)

💊 Product Name	🏭 Manufacturer	🔗 Internal Link
Largactil (Chlorpromazine)	Sanofi India	largactil
Pacitane (Trihexyphenidyl)	Sun Pharma	pacitane
Zyprexa (Olanzapine)	Lilly	zyprexa
Seroquel (Quetiapine)	AstraZeneca	seroquel
Haloperidol (Serenace)	Sun Pharma	serenace
Trifluoperazine (Eskazine)	GlaxoSmithKline	eskazine

📚 External Medical References

🩺 Expert Commentary

Dr. Priya Mehta, Psychopharmacologist:
*”Chlorpromazine’s potent alpha-blockade makes it effective for acute agitation but demands caution in cardiac patients. For maintenance therapy, newer agents like [seroquel] (Quetiapine) offer better metabolic profiles. Always monitor QT interval with doses >100mg/day.”*

📌 Disclaimer

This information does not replace medical advice. Consult a healthcare provider before use. Sun Pharma’s Chlorpromazine is not FDA-approved for hiccups or nausea.

💡 Clinical Pearls:

Emergency Use: IM injection (25–50mg) for acute psychosis (onset: 15–30 min).
Antidote for Overdose: Norepinephrine (NEVER epinephrine due to reversed alpha effects).