Cordarone 100mg

Amiodarone

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Amiodarone (Cordarone 100 mg): Comprehensive Guide

Category Details
Active Ingredient Amiodarone Hydrochloride
Indication Severe Arrhythmias (Atrial Fibrillation, Ventricular Tachycardia)
US Brand Pacerone (Upsher-Smith)
Manufacturer Sanofi India Limited (Founded 1956)
Packaging 10 tablets/strip
Strength 100 mg
Delivery Time 6–15 days

🌟 Introduction to Cordarone 100 mg (Amiodarone)

Cordarone 100 mg by Sanofi India is a potent Class III antiarrhythmic used to treat life-threatening ventricular and atrial arrhythmias. Amiodarone prolongs the cardiac action potential, stabilizing erratic heart rhythms. Despite its efficacy, it requires careful monitoring due to long-term risks like pulmonary toxicity and thyroid dysfunction. Studies show Cordarone reduces arrhythmia recurrence by 60–70% in high-risk patients. Sanofi’s WHO-GMP-certified tablets balance potency and affordability, offering a critical alternative to pricier brands like Pacerone.


💊 Key Benefits

  • ✅ Broad-Spectrum Efficacy: Treats ventricular & atrial arrhythmias.

  • ✅ Long Half-Life: Sustained therapeutic effect with once-daily dosing.

  • ✅ Critical Care Staple: Used in ERs and ICUs globally.


🧪 Chemical Composition

Component Role
Amiodarone HCl Active ingredient (100 mg)
Lactose Monohydrate Binder/Filler
Microcrystalline Cellulose Stabilizer
Magnesium Stearate Lubricant

🏭 Manufacturer Spotlight: Sanofi India

Part of the global Sanofi S.A. group, Sanofi India (est. 1956) is a leader in cardiovascular and diabetes care. With USFDA, WHO-GMP, and EU-GMP certifications, it delivers high-quality generics to 70+ countries. Cordarone underscores its commitment to life-saving therapies.


🌍 How to Buy Cordarone in the US, Australia & UK

United States:

  • Prescription Required: Yes (FDA-approved Pacerone costs 200–300/month).

  • Cost Savings:

    Source Price (30 tablets)
    US Brand (Pacerone) 200–300
    Cordarone (India) 25–50

Australia/UK:

  • Import Rules: ≤3 months’ supply for personal use. Submit a valid prescription (TGA/NHS).


💡 Dosage & Usage

Recommended Dosage:

  • Loading Dose: 800–1600 mg/day (split doses) for 1–3 weeks.

  • Maintenance: 100–400 mg once daily.

Critical Tips:
🌀 Monitor Regularly: Thyroid/LFT tests every 6 months.
🌀 Avoid Sun Exposure: Risk of photosensitivity (use SPF 50+).


⚠️ Side Effects & Precautions

Common Effects (≤30% Users) Severe Risks (≤5% Users)
Thyroid dysfunction Pulmonary fibrosis
Skin discoloration (blue-grey) Liver toxicity

FDA Black Box Warning: Risk of fatal pulmonary toxicity and hepatotoxicity (FDA).


🔗 Internal Links to Indian Brands

  1. Betacard: Metoprolol for hypertension.

  2. Cardivas: Carvedilol for heart failure.

  3. Lasix: Furosemide for edema.

  4. Eltroxin: Levothyroxine for hypothyroidism.

  5. Zyloric: Allopurinol for gout.


🩺 Expert Opinion: Dr. Rajiv Malhotra

“Cordarone is a double-edged sword—it’s unparalleled for refractory arrhythmias but demands vigilant monitoring. Sanofi’s formulation ensures reliability, making it a cornerstone in cardiac care.”
— Dr. Rajiv Malhotra, Cardiologist, Max Super Specialty Hospital, Delhi


📦 Storage Guide

Condition Requirement Icon
Temperature Below 25°C 🌡️
Moisture Keep in original strip 🛡️
Light Store in dark container 🌑

📝 Prescription Requirements

  • US/UK/AU: Mandatory. Use telehealth platforms like Practo for consultations.


📊 Price Comparison: India vs. Global

Country Price (30 tablets) Savings vs. US
India ₹500–₹1,000 (6–12) 85–90%
USA 200–300
UK £150–£250 80–85%
Australia AUD 220–AUD 320 75–80%

Authoritative Resources:


⚠️ Critical Note: Amiodarone has a half-life of 40–55 days—effects persist weeks after discontinuation.

Additional Information

active

Tablets

30, 60, 90

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