Amiodarone (Cordarone 100 mg): Comprehensive Guide
| Category | Details |
|---|---|
| Active Ingredient | Amiodarone Hydrochloride |
| Indication | Severe Arrhythmias (Atrial Fibrillation, Ventricular Tachycardia) |
| US Brand | Pacerone (Upsher-Smith) |
| Manufacturer | Sanofi India Limited (Founded 1956) |
| Packaging | 10 tablets/strip |
| Strength | 100 mg |
| Delivery Time | 6–15 days |
🌟 Introduction to Cordarone 100 mg (Amiodarone)
Cordarone 100 mg by Sanofi India is a potent Class III antiarrhythmic used to treat life-threatening ventricular and atrial arrhythmias. Amiodarone prolongs the cardiac action potential, stabilizing erratic heart rhythms. Despite its efficacy, it requires careful monitoring due to long-term risks like pulmonary toxicity and thyroid dysfunction. Studies show Cordarone reduces arrhythmia recurrence by 60–70% in high-risk patients. Sanofi’s WHO-GMP-certified tablets balance potency and affordability, offering a critical alternative to pricier brands like Pacerone.
💊 Key Benefits
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✅ Broad-Spectrum Efficacy: Treats ventricular & atrial arrhythmias.
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✅ Long Half-Life: Sustained therapeutic effect with once-daily dosing.
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✅ Critical Care Staple: Used in ERs and ICUs globally.
🧪 Chemical Composition
| Component | Role |
|---|---|
| Amiodarone HCl | Active ingredient (100 mg) |
| Lactose Monohydrate | Binder/Filler |
| Microcrystalline Cellulose | Stabilizer |
| Magnesium Stearate | Lubricant |
🏭 Manufacturer Spotlight: Sanofi India
Part of the global Sanofi S.A. group, Sanofi India (est. 1956) is a leader in cardiovascular and diabetes care. With USFDA, WHO-GMP, and EU-GMP certifications, it delivers high-quality generics to 70+ countries. Cordarone underscores its commitment to life-saving therapies.
🌍 How to Buy Cordarone in the US, Australia & UK
United States:
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Prescription Required: Yes (FDA-approved Pacerone costs 200–300/month).
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Cost Savings:
Source Price (30 tablets) US Brand (Pacerone) 200–300 Cordarone (India) 25–50
Australia/UK:
💡 Dosage & Usage
Recommended Dosage:
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Loading Dose: 800–1600 mg/day (split doses) for 1–3 weeks.
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Maintenance: 100–400 mg once daily.
Critical Tips:
🌀 Monitor Regularly: Thyroid/LFT tests every 6 months.
🌀 Avoid Sun Exposure: Risk of photosensitivity (use SPF 50+).
⚠️ Side Effects & Precautions
| Common Effects (≤30% Users) | Severe Risks (≤5% Users) |
|---|---|
| Thyroid dysfunction | Pulmonary fibrosis |
| Skin discoloration (blue-grey) | Liver toxicity |
FDA Black Box Warning: Risk of fatal pulmonary toxicity and hepatotoxicity (FDA).
🔗 Internal Links to Indian Brands
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Betacard: Metoprolol for hypertension.
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Cardivas: Carvedilol for heart failure.
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Lasix: Furosemide for edema.
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Eltroxin: Levothyroxine for hypothyroidism.
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Zyloric: Allopurinol for gout.
🩺 Expert Opinion: Dr. Rajiv Malhotra
“Cordarone is a double-edged sword—it’s unparalleled for refractory arrhythmias but demands vigilant monitoring. Sanofi’s formulation ensures reliability, making it a cornerstone in cardiac care.”
— Dr. Rajiv Malhotra, Cardiologist, Max Super Specialty Hospital, Delhi
📦 Storage Guide
| Condition | Requirement | Icon |
|---|---|---|
| Temperature | Below 25°C | 🌡️ |
| Moisture | Keep in original strip | 🛡️ |
| Light | Store in dark container | 🌑 |
📝 Prescription Requirements
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US/UK/AU: Mandatory. Use telehealth platforms like Practo for consultations.
📊 Price Comparison: India vs. Global
| Country | Price (30 tablets) | Savings vs. US |
|---|---|---|
| India | ₹500–₹1,000 (6–12) | 85–90% |
| USA | 200–300 | — |
| UK | £150–£250 | 80–85% |
| Australia | AUD 220–AUD 320 | 75–80% |
Authoritative Resources:
⚠️ Critical Note: Amiodarone has a half-life of 40–55 days—effects persist weeks after discontinuation.





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