Name: Flucort N
SKU: 23460
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredients:	Fluocinolone Acetonide 0.025% w/w, Neomycin Sulfate 0.5% w/w
💊 Indication:	Infected Inflammatory Dermatoses (Eczema, Dermatitis)
🇺🇸 US Brand Equivalent:	Cortisporin Cream (Hydrocortisone/Neomycin) – no direct equivalent
🏭 Manufacturer:	Glenmark Pharmaceuticals Ltd (Founded: 1977)
📦 Packaging:	20 g Tube
🧪 Strength:	Fluocinolone 0.025% / Neomycin 0.5%
🚚 Delivery Time:	6–15 days

🌿 What is Flucort N Cream 0.025%/0.5%?

Flucort N Cream combines Fluocinolone Acetonide, a low- to mid-potency topical corticosteroid, with Neomycin Sulfate, an aminoglycoside antibiotic. This combination addresses inflammatory skin conditions complicated by secondary bacterial infection. Fluocinolone reduces erythema, itching, and inflammation by modulating cytokine production in skin cells. Neomycin provides bactericidal activity against Gram-negative and some Gram-positive bacteria by inhibiting protein synthesis. Flucort N’s emollient cream base ensures rapid absorption, soothing hydrating properties, and minimizes irritation, making it suitable for localized acute or chronic infected inflammatory dermatoses.

🧬 Pharmacology & Mechanism of Action

Component	Mechanism
Fluocinolone Acetonide 0.025%	• Binds glucocorticoid receptors → modulates gene transcription → decreases inflammatory cytokines (IL-1, TNF-α) → vasoconstriction reduces erythema, edema, and pruritus.
Neomycin Sulfate 0.5%	• Binds to 30S ribosomal subunit → interrupts initiation complex formation → inhibits bacterial protein synthesis → bactericidal against susceptible organisms.
Cream Base	• Emollient, water-in-oil emulsion → enhances drug penetration, provides occlusive effect, and maintains skin hydration.

💡 Indications & Application Guidelines

Condition	Application Regimen
Infected Eczematous Dermatitis	• Cleanse and gently pat dry affected area. • Apply a thin layer of Flucort N Cream to lesions 2–3 times daily. • Duration: Use for up to 10 days; reassess for continued need.
Impetiginized Psoriasis or Dermatitis (Localized)	• Clean lesion; apply thinly twice daily. • Continue therapy for 7–14 days, depending on bacterial clearance.
Skin Infections with Inflammatory Component	• Apply cream to infected inflammatory lesions twice daily for 5–7 days or until infection resolves. • After resolution, switch to corticosteroid monotherapy if inflammation persists.

Preparation: Prior to application, cleanse with mild non-antiseptic soap and water; pat dry.
Application: Squeeze appropriate amount; spread evenly over lesion and 1 cm margin.
Frequency: Typically, 2–3 times daily based on severity.
Precautions: Do not use under occlusive dressings unless directed by a healthcare provider.
Children & Elderly: Use lowest effective frequency; monitor for signs of systemic absorption.

⚠️ Warnings & Side Effects

Common (Local):

Transient burning or stinging at application site
Mild dryness or peeling
Erythema (paradoxical)

Less Common:

Skin atrophy, striae, or telangiectasia with prolonged corticosteroid use
Folliculitis
Contact dermatitis (allergic) to Neomycin or excipients

Serious (Rare):

Hypothalamic-Pituitary-Adrenal (HPA) Axis Suppression (with extensive use)
Neomycin-induced ototoxicity or nephrotoxicity (systemic absorption very unlikely but caution in large areas)
Superinfection with resistant organisms (e.g., Pseudomonas)

Precautions:

Hypersensitivity: Contraindicated in patients with known allergy to aminoglycosides or corticosteroids.
Pre-existing Viral Infections: Avoid use in viral lesions (e.g., herpes simplex) unless directed.
Occlusive Dressings: Avoid unless under specialist care due to increased absorption and risk of side effects.
Monitoring: If treated area exceeds 20% of body surface or used >2 weeks, monitor for systemic corticosteroid effects.
Pregnancy & Lactation: Use only if potential benefits justify potential risks; neomycin passes poorly through intact skin.

🏥 Storage Instructions

Store Flucort N Cream at 20°C–25°C (68°F–77°F) in a cool, dry place. Protect from excessive heat and direct sunlight. Ensure cap is tightly closed after each use. Discard 3 months after opening. Keep out of reach of children.

🌐 Availability & Purchasing

United States: No direct combination product; prescription-based import; separate topical corticosteroids and Neomycin creams available.
United Kingdom & EU: Prescription required; combination corticosteroid/antibiotic formulations available under dermatology guidance.
Australia: Prescription necessary; import permitted under TGA guidelines with valid prescription.

Importing Flucort N from India:
Purchasing Flucort N Cream from India can reduce costs. Ensure you hold a valid prescription, comply with local import regulations, and verify product authenticity to avoid customs delays.

🔗Authoritative Resources

🔗Related Topical Therapies (Indian Brands)

Betnovate N Cream (Betamethasone/Neomycin) – Betamethasone + Neomycin by GSK India.
Fucicort Cream – Fusidic Acid + Betamethasone by Sun Pharma.
Flutibact Ointment – Fluticasone + Mupirocin by GSK India.

🎥 Educational Video on Combination Antibiotic/Corticosteroid Therapy

👨‍⚕️ Expert Insight: Dr. Meera Joshi, Dermatologist

“Flucort N Cream’s dual action effectively targets both inflammation and secondary bacterial infection in dermatitis. Proper duration and monitoring are key to minimize corticosteroid-related skin thinning and antibiotic resistance.”