Name: Fosirol Powder
SKU: 7786
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Fosfomycin Tromethamine
💊 Indication:	Uncomplicated Urinary Tract Infections (UTIs)
🇺🇸 US Brand:	Monurol
🏭 Manufacturer:	Cipla Limited (Founded: 1935)
📦 Packaging:	1 Sachet per Pack
🧪 Strength:	3 g (Net wt: 8gm)
🚚 Delivery Time:	6–15 days

🌿 What is Fosfomycin 3 g (Fosirol Powder)?

Fosirol Powder contains Fosfomycin Tromethamine, a broad-spectrum bactericidal antibiotic that inhibits bacterial cell wall synthesis by blocking the MurA enzyme. It is indicated for the treatment of uncomplicated UTIs, including cystitis in women.

A single 3 g oral dose achieves high urinary concentrations, maintaining bactericidal levels for 48–72 hours. This single-dose regimen enhances patient compliance and reduces resistance risk.

For full prescribing information and safety data, refer to the FDA label for Monurol and the Drugs.com monograph. Additional guidance is available via the NHS Medicines A–Z entry and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C3H7O4P
Molecular Weight	138.06 g/mol
Bioavailability	~34–41%
Metabolism	Not metabolized; excreted unchanged in urine
Half-Life	~5–6 hours

Fosfomycin’s unique mechanism targets early cell wall synthesis steps, making it active against MDR organisms.

💡 Indication & Dosing

Condition	Dose & Administration
Uncomplicated UTI (Cystitis)	Single 3 g sachet dissolved in water, taken orally once; avoid food or drink 3 hours before and after dosing

Ensure adequate hydration. Do not repeat dose without medical advice.

⚠️ Warnings & Side Effects

Common:

Diarrhea
Nausea
Headache

Serious (rare):

Hypersensitivity reactions (rash, anaphylaxis)
Clostridioides difficile-associated diarrhea

Monitor for GI symptoms and allergic reactions. Use caution in patients with renal impairment.

🏥 Storage Instructions

Store Fosirol Powder at 20–25°C in original sachet. Protect from moisture. Use immediately after reconstitution.

🌐 Global Availability & Purchasing

USA: Prescription-only (Monurol); single-dose sachet.
UK & EU: Prescription required; generic fosfomycin available.
Australia: Prescription and TGA approval required.

Importing from India may reduce costs; ensure regulatory compliance and hold a valid prescription.

🔗 Related UTI Therapies

Nitrofurantoin 100 mg – UTI antibiotic.

🎥 Educational Video on Fosfomycin

👨‍⚕️ Expert Insight: Dr. Shweta Kulkarni, Infectious Disease Specialist

“Fosfomycin’s single-dose efficacy improves adherence and offers a valuable option for outpatient UTI management, especially in the era of rising resistance.”