Hydroquinone 4% Cream
Tyrosinase inhibitor for melasma, post-inflammatory hyperpigmentation, and stubborn dark spots.
Formulated in a moisturizing, hypoallergenic cream base for facial and body application.
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What is Hydroquinone 4% Cream?
Hydroquinone 4% is the gold-standard topical depigmenting agent for treating moderate-to-severe hyperpigmentation.
It works by inhibiting tyrosinase, the key enzyme in melanin synthesis, reducing epidermal melanin production.
This Abbott formulation (30g tube) delivers consistent 4% concentration in a cosmetically elegant, hypoallergenic cream base.
📦 Product Specifications
Hydroquinone 4% Cream
Hydroquinone 4% w/w
4% (40 mg/g)
30g aluminum tube • Sealed
Abbott Laboratories (Healthcare)
Topical cream • Smooth, non-greasy base
Visible lightening in 4–8 weeks
Rx only in most countries
🧴 Mechanism & Application Protocol
Tyrosinase Inhibition
Hydroquinone competitively inhibits tyrosinase, blocking conversion of tyrosine to melanin.
This reduces melanin production in hyperactive melanocytes without affecting normal skin.
Abbott Moisturizing Base
Formulated with emollients and stabilizers to minimize irritation, enhance absorption, and maintain skin barrier integrity during treatment.
Sun Protection Mandatory
UV exposure reverses melanin suppression. Daily SPF 50+ sunscreen is essential throughout treatment and maintenance phases.
🩺 Indications & Clinical Use
Primary Indications
- Melasma (chloasma)
- Post-inflammatory hyperpigmentation (acne, eczema, trauma)
- Solar lentigines (age spots, liver spots)
- Freckles (ephelides)
- Refractory hyperpigmentation unresponsive to OTC agents
Combination Therapy
- + Tretinoin (enhanced penetration & turnover)
- + Mild corticosteroid (reduces irritation)
- Kligman formula: hydroquinone + tretinoin + steroid
- Alternating with azelaic acid or kojic acid for maintenance
Diagnosis and treatment should be supervised by a dermatologist. Use only on hyperpigmented areas, avoiding healthy surrounding skin.
📋 Application Guidelines
| Parameter | Recommendation |
|---|---|
| Application Frequency | Thin layer twice daily (morning and evening) or as prescribed |
| Treatment Cycle | 8–12 weeks continuous use, followed by 4–8 week washout period |
| Sun Protection | Broad-spectrum SPF 50+ every morning, reapply every 2–3 hours |
| Combination Agents | Tretinoin at night (if tolerated) to enhance efficacy |
| Maintenance | After cycle, switch to non-hydroquinone brighteners (azelaic acid, kojic acid, vitamin C) |
Always apply only to affected areas. Avoid contact with eyes, lips, and mucous membranes. Discontinue if severe irritation occurs.
⚠️ Contraindications & Critical Warnings
Special Precautions: Perform a patch test before first application. Use only on hyperpigmented lesions — not on normal skin.
Discontinue if severe erythema, burning, or allergic reaction occurs. Exogenous ochronosis (blue-black discoloration) is rare but associated with prolonged continuous use beyond 4–6 months.
Strictly adhere to treatment cycles. Monitor for paradoxical darkening in some patients.
📋 Common Side Effects
- Mild erythema / transient redness
- Dryness or slight peeling
- Mild stinging or burning sensation
- Contact dermatitis (rare)
- Paradoxical hyperpigmentation (uncommon)
- Exogenous ochronosis (rare, with prolonged use)
Most side effects are mild and transient. Reduce frequency to once daily if irritation occurs. Discontinue if severe.
🧴 Storage & Handling
Temperature
Store at 15–30°C (room temperature). Do not freeze. Protect from direct sunlight.
Tube Integrity
Keep tube tightly closed after each use. Do not use if seal is broken.
Shelf Life
Stable until expiration date printed on tube crimp. Discard 6 months after opening.
🚚 International Shipping — Discreet & Tracked
🇦🇺 Australia Shipping
- Delivery: 7-14 business days
- Tracking: Full tracking provided
- Packaging: Discreet, sealed
🇺🇸 United States Shipping
- Delivery: 5-12 business days
- Tracking: USPS / UPS tracking
- Insured: Full package protection
🇬🇧 United Kingdom Shipping
- Delivery: 6-12 business days
- Tracking: Royal Mail tracking
- Guarantee: Reshipment if lost or damaged
✓ Guaranteed delivery to Australia, United States, and United Kingdom
All orders shipped with discreet packaging and full tracking. Temperature-controlled shipping available upon request.
Order Hydroquinone 4% Cream — Abbott 30g
Pharmaceutical-grade skin depigmenting cream. 4% hydroquinone in a gentle moisturizing base.
Trusted Abbott formulation. ✓ We ship to Australia, United States, and United Kingdom with discreet, tracked shipping.
✓ Guaranteed delivery to Australia, United States, and United Kingdom • Discreet packaging • Fully tracked • Reshipment guarantee
🛒 Related Products
⚠️ Important Medical Information
Hydroquinone 4% is a prescription medicine — must be used under dermatologist supervision.
Contraindicated in pregnancy, lactation, active skin infections, and known hypersensitivity.
Exogenous ochronosis risk with prolonged continuous use beyond 4–6 months.
Always use broad-spectrum SPF 50+ sunscreen during treatment.
Perform a patch test before first application.
Discontinue if severe irritation, burning, or allergic reaction occurs.
International shipping: Importing prescription medications may be restricted; you are responsible for local laws.
This information is for educational purposes only. Abbott is a registered trademark. BuyAllMD.com is an independent distributor.
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