โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Imiquimod |
|---|---|
| ๐ Indication: | Actinic Keratosis, Superficial Basal Cell Carcinoma, External Genital Warts |
| ๐บ๐ธ US Brand: | Aldara |
| ๐ญ Manufacturer: | Glenmark Pharmaceuticals Ltd. (Founded: 1977) |
| ๐ฆ Packaging: | 0.25 g Sachet |
| ๐งช Strength: | 5% w/w |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What is Imiquimod 5% (Imiquad Sachet)?
Imiquad Sachet delivers a 5% imiquimod cream in pre-measured 0.25 g packets designed for precise topical application. Imiquimod is an immune response modifier that stimulates Toll-like receptor 7, inducing cytokines (IFN-ฮฑ, TNF-ฮฑ, IL-12) to promote antiviral and antitumor activity.
This mechanism harnesses the bodyโs innate immunity to clear abnormal skin cells and viral infections. Actinic keratoses patients experience gradual lesion erythema and resolution over weeks, while genital wart treatment leads to wart regression via localized immune activation. Imiquadโs sachet format ensures accurate dosing, minimizes waste, and enhances patient adherence.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C14H16N4O3 |
| Molecular Weight | 240.31 g/mol |
| Mode of Action | TLR7 agonist โ cytokine induction โ immune-mediated clearance |
| Local Activity | Induces apoptosis in dysplastic/viral-infected cells |
๐ก Indications & Application Guidelines
| Condition | Regimen |
|---|---|
| Actinic Keratosis (AK) | Apply 5% cream 3ร weekly for 4 weeks; wash off after 8โ10 hrs |
| Superficial BCC | Apply 5% cream 5ร weekly for 6 weeks; wash off after 8โ10 hrs |
| External Genital Warts (AGW)** | Apply 5% cream 3ร weekly for up to 16 weeks; wash off after 6โ10 hrs |
Use gloves to avoid mucosal exposure. Schedule treatments to minimize irritation and monitor local skin reactions.
โ ๏ธ Warnings & Side Effects
Common:
- Local skin reactions: erythema, erosion, pruritus, edema
- Flu-like symptoms (rare)
Serious (rare):
- Severe local inflammation requiring treatment interruption
- Systemic symptoms: fever, myalgia, lymphadenopathy
Advise patients on expected erythema and treatment pauses if severe erosions develop. Contraindicated in immunocompromised individuals without specialist oversight.
๐ฅ Storage Instructions
Store Imiquad Sachets at 20โ25ยฐC. Protect from light and moisture. Keep packets sealed until use and out of reach of children.
๐ Availability & Purchasing
- USA: Prescription-only (Aldara); compounding alternatives available.
- UK & EU: Prescription required; generic imiquimod formulations accessible.
- Australia: Schedule 4; prescription use only.
Glenmarkโs sachet format offers cost-effective dosing. Ensure compliance with local guidelines and specialist prescription.
๐ฅ Educational Video on Imiquimod Therapy
๐จโโ๏ธ Expert Insight: Dr. Meera Rao, Dermatologist
โImiquadโs sachet dosing ensures precise imiquimod delivery, optimizing efficacy and minimizing waste. Patient education on expected local reactions drives adherence and successful outcomes.โ




