โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Ketoprofen 100 mg |
|---|---|
| ๐ Indication: | Relief of Acute and Chronic Musculoskeletal Pain (Sprains, Strains, Osteoarthritis) |
| ๐บ๐ธ US Brand: | Flector Patch (Diclofenac) โ analogous topical patch concept |
| ๐ญ Manufacturer: | Zuventus Healthcare (Founded: 1991) |
| ๐ฆ Packaging: | 7 Transdermal Patches per Packet |
| ๐งช Strength: | 30 mg per patch (Ketoprofen) |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What is Ketoprofen 100 mg Transdermal Patch (Ketoplast Plus)?
Ketoplast Plus delivers 100 mg of Ketoprofen per patch through the skin, providing sustained, localized NSAID therapy directly to affected tissues. It inhibits COX-1 and COX-2 enzymes in underlying muscles and joints, reducing inflammation and pain without significant systemic exposure.
For detailed prescribing information, safety profiles, and application guidelines, consult the Drugs.com monograph on topical ketoprofen, the NHS Medicines AโZ entry, and the WHO Essential Medicines List.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C16H14O3 |
| Molecular Weight | 254.28 g/mol |
| Permeation | Enhanced transdermal diffusion via matrix patch |
| Metabolism | Minimal systemic absorption; hepatic if absorbed |
| Duration of Effect | Continuous delivery over 24 hours |
Ketoprofen blocks prostaglandin synthesis locally, attenuating inflammatory mediators and providing sustained analgesia.
๐ก Indications & Application
- Sprains & Strains: Apply one patch to intact skin over the painful area once daily.
- Osteoarthritis: Use patches on large joint surfaces, replace every 24 hours.
- Chronic Musculoskeletal Pain: Patches can be applied consecutively for up to 7 days; monitor skin condition.
Do not apply to broken or inflamed skin. Rotate patch sites to minimize skin irritation.
โ ๏ธ Warnings & Side Effects
Common (Local):
- Skin irritation, erythema
- Itching, burning sensation
Serious (Rare):
- Contact dermatitis
- Photosensitivity reactions
Discontinue if severe dermatitis occurs. Avoid exposure to sunlight on applied area. Do not use occlusive dressings.
๐ฅ Storage Instructions
Store Ketoplast Plus patches at 20โ25ยฐC. Protect from moisture and direct sunlight. Keep in sealed packet until use.
๐ Availability & Purchasing
- USA: Topical ketoprofen patches not available; diclofenac patch Flector as alternative.
- UK & EU: Some markets offer ketoprofen patches by prescription.
- Australia: Prescription topical patches available; check TGA approval.
International import may reduce costs; ensure regulatory compliance and hold valid prescription.
๐ Related Topical and Transdermal Analgesics
- Fastum Gel 2.5% โ ketoprofen topical gel.
๐ฅ Educational Video on Transdermal NSAID Therapy
๐ฉโโ๏ธ Expert Insight: Dr. Rakesh Jain, Rheumatologist
โKetoplast Plus patches offer continuous, targeted NSAID delivery without peaks and troughs of oral dosing. Theyโre especially useful in chronic joint pain and acute injuries when systemic NSAIDs pose risks.โ




