Ketorol Gel

Ketorolac

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Ketorol Gel
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Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name): Ketorolac Tromethamine 4%
💊 Indication: Topical treatment of acute musculoskeletal pain, sprains, strains, and soft tissue injuries
🇺🇸 US Brand: Toradol Topical
🏭 Manufacturer: Dr. Reddy’s Laboratories Ltd (Founded: 1984)
📦 Packaging: 30 g Tube
🧪 Strength: 4% (40 mg/g) Ketorolac Tromethamine
🚚 Delivery Time: 6–15 days

🌿 What is Ketorolac 4% Gel (Ketorol Gel)?

Ketorol Gel contains 4% Ketorolac Tromethamine formulated for topical application. It delivers targeted NSAID therapy directly to the site of acute musculoskeletal pain, reducing inflammation and pain without the systemic exposure associated with oral or injectable NSAIDs.

For prescribing information, safety data, and contraindications, see the FDA label for Topical Ketorolac, the Drugs.com topical NSAIDs guide, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.


🧬 Pharmacology & Mechanism of Action

Attribute Detail
Chemical Formula C15H13NO3
Molecular Weight 255.27 g/mol
Permeation Skin penetration optimized for local effect
Metabolism Minimal systemic absorption; hepatic if absorbed
Half-Life Local effect duration ~4–6 hours

Ketorolac inhibits COX enzymes locally in inflamed tissues, reducing prostaglandin synthesis and pain signaling.


💡 Indications & Application

  • Acute Musculoskeletal Pain: Apply a thin layer to the affected area 3–4 times daily.
  • Sprains & Strains: Massage gently until absorbed.
  • Soft Tissue Injuries: Continue use for up to 7 days; not for chronic pain.

Wash hands before and after application; avoid contact with eyes or mucous membranes.


⚠️ Warnings & Side Effects

Common (Local):

  • Mild skin irritation, erythema
  • Pruritus

Serious (Rare):

  • Contact dermatitis
  • Photosensitivity reactions
  • Systemic NSAID effects if overused or on large areas

Avoid use on open wounds, infections, or areas with impaired skin integrity. Do not occlude treated area. Discontinue if severe skin reaction occurs.


🏥 Storage Instructions

Store Ketorol Gel at 20–25°C. Protect from freezing and direct sunlight. Keep tube tightly closed and out of reach of children.


🌐 Availability & Purchasing

  • USA: Prescription-only topical NSAID; limited availability.
  • UK & EU: Prescription required; topical ketorolac available in some markets.
  • Australia: Prescription and TGA approval required.

Importing from India offers cost savings; ensure regulatory compliance and valid prescription.


🔗 Related Topical Analgesics


🎥 Educational Video on Topical NSAIDs


👩‍⚕️ Expert Insight: Dr. Rahul Mehta, Rheumatologist

“Topical Ketorolac gel offers targeted relief in acute soft tissue injuries, minimizing systemic risk. It’s a valuable addition to multimodal pain management in outpatient settings.”


Additional Information

Active

Ketorolac

Gel/s

1, 3, 6

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