Name: Levipil 500mg
SKU: 14175
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Levetiracetam
💊 Indication:	Epilepsy (Adjunctive Therapy for Partial-Onset Seizures, Myoclonic Seizures, Primary Generalized Tonic-Clonic Seizures)
🇺🇸 US Brand:	Keppra
🏭 Manufacturer:	Sun Pharmaceutical Industries Ltd. (Founded: 1993)
📦 Packaging:	10 Tablets per Strip
🧪 Strength:	500 mg
🚚 Delivery Time:	6–15 days

🌿 What is Levetiracetam 500 mg (Levipil)?

Levipil contains Levetiracetam, a novel anticonvulsant with a unique mechanism: it binds to synaptic vesicle protein 2A (SV2A), modulating neurotransmitter release and reducing neuronal hyperexcitability. It is used as adjunctive therapy for various seizure types, offering broad-spectrum efficacy and a favorable safety profile.

Clinical trials indicate that Levetiracetam 500 mg twice daily significantly reduces seizure frequency in refractory epilepsy, with rapid onset of action and minimal drug-drug interactions. Its renal excretion and minimal hepatic metabolism make it suitable for polytherapy situations.

For complete prescribing and safety information, refer to the FDA label for Keppra and the Drugs.com monograph. Additional guidance is available via the NHS Medicines A–Z entry and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Bioavailability	~100% (oral)
Metabolism	Minimal hepatic (CYP-independent)
Half-Life	~6–8 hours

Levetiracetam’s binding to SV2A modulates synaptic vesicle release, dampening excitatory transmission without significant interaction with other AEDs.

💡 Indications & Dosing

Condition	Dose & Administration
Partial-Onset Seizures (adjunctive)	Start 500 mg twice daily; may increase by 500 mg every 2 weeks to 1,000–3,000 mg/day in divided doses
Myoclonic Seizures (adjunctive in JME)	500 mg twice daily; may increase to 1,500 mg twice daily as needed
Primary Generalized Tonic-Clonic Seizures (adjunctive)	500 mg twice daily; titrate per response up to 3,000 mg/day

Dosing adjustments required in renal impairment. Generally well-tolerated with twice-daily regimen.

⚠️ Warnings & Side Effects

Common:

Somnolence, asthenia
Dizziness, headache
Behavioral changes (irritability)

Serious:

Psychiatric symptoms (depression, psychosis)
Anaphylaxis (rare)
Suicidal ideation

Monitor mood and behavior due to neuropsychiatric effects. Adjust dose for renal function and monitor renal parameters.

🏥 Storage Instructions

Store Levipil 500 mg at 20–25°C in original blister packaging. Protect from moisture and light.

🌐 Availability & Purchasing

USA: Prescription-only (Keppra); generics available.
UK & EU: Prescription required; Levipil and generics.
Australia: Prescription and TGA approval required.

Importing from India may provide cost savings; ensure regulatory compliance and valid prescription.

🔗 Related Antiepileptic Drugs

Carbamazepine 200 mg – sodium channel blocker.

🎥 Educational Video on Levetiracetam

👩‍⚕️ Expert Insight: Dr. Suresh Iyer, Epileptologist

“Levetiracetam’s unique SV2A binding and minimal interaction profile make Levipil 500 mg an excellent adjunctive AED, particularly in polytherapy. Monitor for behavioral changes.”