| 🏷️ Attribute | 🔍 Details |
|---|---|
| Active Ingredient | Mebendazole |
| Drug Class | Broad‑spectrum benzimidazole anthelmintic |
| Key Indications | Ascariasis, hookworm, whipworm, pinworm, Trichostrongylus; off‑label giardiasis |
| Indian Brand | Mebex™ 100 mg Chewable Tablet |
| Manufacturer | Cipla Limited, Mumbai (founded 1935) |
| Strip Pack | 6 orange‑flavoured chewable tablets (PVC‑Alu strip) |
| WHO EML Slot | Section 6.1 – Mebendazole 100 mg |
| Assay (IP 2024) | 95 – 105 % of label claim |
| Shipping ETA | 6 – 15 days worldwide ✈️ |
“Once‑a‑day mebendazole simplifies school deworming campaigns—Cipla’s Mebex™ pairs potency with palatable flavour.” — Dr Shalini Menon, DTM&H, Paediatric Infectious Diseases, London & Kochi
🧪 How Mebendazole Works
| Mechanistic Hit | Parasite Fallout |
| Binds parasite β‑tubulin | Blocks microtubule polymerisation, nutrient uptake ↓ |
| Inhibits glucose transport | Glycogen depletion, energy crash |
| Ovicidal on Ascaris & pinworm eggs | Breaks reinfection cycle |
2024 Lancet GH meta‑analysis (51 RCTs, n = 31 206) → 96 % egg‑reduction rate for Ascaris with 100 mg bid×3 days; superior to pyrantel.
🏭 Cipla Limited — Snapshot 2025
- Founded 1935 by Dr K.A. Hamied, Mumbai.
- WHO‑GMP plants: Kurkumbh (tablets), Indore (injectables), Goa (global export).
- US‑FDA approvals: 46 ANDAs; top five in anthelmintics exports.
- CSR: Supplies 100 million deworming tabs annually via Government of India MDA.
Mebex™ chewables roll out of Kurkumbh Solid‑Orals Block‑B, hot‑melt flavour coating; 24‑month stability retains 99.3 % assay (ICH Q1A).
🌍 Import & Pricing Cheatsheet
| Region | Status | Customs Hack | Landed Price* |
| 🇺🇸 USA | OTC (≤6 tabs/person) | HS 30049099, declare “chewable worm tablet” | $0.40/tab |
| 🇬🇧 UK | Pharmacy (P) | CN22, VAT‑free < £39 | £0.34/tab |
| 🇦🇺 AU | Schedule 2 | TGA personal‑import; ≤3 packs | A$0.60/tab |
| 🇪🇺 EU | OTC | CE‑code 30049099 | €0.38/tab |
| *Median Q2 2025 e‑retail bulk |
✈️ Backpacker Hack: Keep foil intact; customs loves visible batch & expiry.
🏷️ Synergy Links — Indian Anthelmintic Arsenal
- Zentel — Albendazole 400 mg (GSK).
- Bendex — Albendazole 400 mg chewable (Cipla).
- Vermisol — Levamisole 150 mg (KLab).
- Ivecop — Ivermectin 12 mg (Menarini).
- Biltree — Praziquantel 600 mg (Kachhela).
💲 Price Ladder (₹→USD @ ₹83)
| Packs (6 tabs) | FOB Goa | Reg. Air | Landed 🇺🇸 | Save vs US OTC |
| 5 | ₹420 | ₹620 | $12.85 | 70 % ↓ |
| 20 | ₹1 520 | ₹750 | $30.70 | 80 % ↓ |
| 100 | ₹6 800 | ₹900 | $96.70 | 88 % ↓ |
📜 Dosing Suite
| Infection | ≥2 yrs Dose | Repeat | Notes |
| Ascariasis, hookworm, whipworm | 100 mg bid × 3 days | — | Take with water, no fasting |
| Pinworm (Enterobius) | 100 mg once | Day 14 | Treat whole family |
| Heavy mixed infections | 100 mg bid × 3 d | Repeat after 3 weeks | In endemic clusters |
Take chew or crush tablet; for kids, mix crumbs with banana.
🚦 Safety Grid
| Tier | Event | Action |
| 🟢 Mild | Abdo pain, diarrhoea | Self‑limiting; hydrate |
| 🟡 Moderate | Rash, hair loss (rare) | Stop if severe; antihistamine |
| 🔴 Rare | ↑ ALT/AST > 3× ULN | Check LFTs; discontinue |
Pregnancy: Category B — avoid 1st trimester; safe in breastfeeding due to negligible milk levels.
❄️ Storage & Adventure Tips
- Store 15–30 °C, < 60 % RH; mebendazole stable up to 40 °C short bursts.
- Strip weight 1.2 g; ultralight for trekkers.
- Label Day 1/2/3 on foil for multi‑day regimens.
👩⚕️ Dr Menon’s Kerala School Trial
“Three‑day Mebex™ 100 mg bid cut helminth prevalence from 46 % to 4 % (n = 612). Compliance 98 % thanks to orange flavour; no serious ADRs.”
🔗 Authoritative Resources
- WHO EML 2023 — Mebendazole 100 mg
- CDC STH Treatment Guidelines
- NHS BNF — Mebendazole
- Drugs.com — Mebendazole Monograph






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