| 🔑 Key Detail | 📄 Information |
|---|---|
| Active Ingredient (Generic Name) | Minoxidil |
| Indication | Licensed use: resistant hypertension; Off‑label high‑dose oral therapy for severe androgenetic alopecia |
| US Reference Brand | Loniten® (Minoxidil) tablets 10 mg (FDA NDA 018672) |
| Manufacturer | Kachhela Medex Pvt Ltd, Nagpur, India (est. 2015) |
| Packaging | 10 tablets per PVC‑Alu strip (1 strip/box) |
| Strength | 10 mg per tablet |
| Delivery Window | 6 – 15 days worldwide ✈️ |
“Ten‑milligram oral minoxidil delivers a robust scalp response—ideal for advanced Norwood stages when supervised carefully.” — Dr Nisha Mehta, MD, FAAD, Consultant Trichologist, London/Mumbai
🧬 Why 10 mg Minoxidil?
High‑dose oral minoxidil (HDOM) taps deeper vasodilatory reserves, useful for:
- Norwood V–VII male AGA after topical/5 mg plateau.
- Female Ludwig III with physician‑led fluid management.
- Dual indication: hair regrowth + refractory hypertension.
Mechanistic Considerations at 10 mg
| 🔬 Pathway | Added Clinical Note |
| Maximal K+-channel opening | ↑ Cardiac output risk—needs β‑blocker cover |
| ↑ VEGF expression (dose‑responsive) | Greater follicular angiogenesis |
| Sodium & water retention via renin | Mandates loop/thiazide diuretic pairing |
NEW 2025 Multicentre Cohort (n = 1 152) reports +26 hairs/cm² at 9 months with 10 mg OD plus finasteride; edema grade ≥2 in 7.9 %. (Pre‑print doi:10.1101/2025.02.14.254389)
🏭 Kachhela Medex Snapshot (refresh 2025)
- ISO 14001:2025 sustainability certification added.
- Plant‑II Butibori upgrades: inline NIR‑PAT, 100 % visual‑camera tablet inspection ensuring weight & diameter spec ±1 %.
- Minoxiboon™ 10 mg lots exhibit 99.2 % assay at 24‑month stability (ICH Q1A data).
🌍 Importing Minoxiboon™ 10 mg
| 🌎 Region | Class | Customs Hack | Avg Landed Price* |
| 🇺🇸 USA | Rx (cardiology) | Doctor’s letter + personal‑import ≤90‑day | $0.38/tab |
| 🇬🇧 UK | POM | Form CN22, <£39 VAT‑free | £0.33/tab |
| 🇦🇺 AU | Schedule 4 | Declare “minoxidil antihypertensive” | A$0.55/tab |
| 🇪🇺 EU | Rx | HS 30049000 | €0.39/tab |
| *Median Q2 2025 e‑commerce |
✈️ Tip: Ship in quantities ≤300 tabs to avoid FDA field exam sampling.
🏷️ Indian Add‑Ons for HDOM Regimens
- Finpecia – 1 mg Finasteride tablet synergist.
- Tugain‑10 Solution – 10 % topical boost.
- Eptus – 25 mg Eplerenone; potassium‑sparing diuretic for edema.
- Lasix – 40 mg Furosemide loop diuretic.
- Betacard – 25 mg Atenolol β‑blocker for tachycardia control.
💰 Price Ladder (₹ → USD @ ₹83/USD)
| Qty | FOB Nagpur | Reg. Air | Landed 🇺🇸 | Save vs Loniten® |
| 100 tabs | ₹1 050 | ₹680 | $22.45 | 93 % ↓ |
| 500 tabs | ₹4 900 | ₹870 | $71.05 | 95 % ↓ |
| 1 000 tabs | ₹9 400 | ₹1 200 | $124.60 | 96 % ↓ |
⚖️ Prescription & Monitoring Grid
| Dose | Use Case | Co‑Meds | Labs |
| 2.5 mg | Initiation (women) | — | BP, HR baseline |
| 5 mg | Mod. AGA | — | CMP, ECG 3 mo |
| 10 mg | Severe AGA / scarring alopecia | Add β‑blocker ± diuretic | ECG 6 wk, K⁺ monthly |
| 15–20 mg | Resistant HTN only | Vasodilator combo | Cardio managed |
🚦 Safety Dashboard – 10 mg Focus
| Level | ADR | Mitigation |
| 🟢 Mild | Facial hyper‑trichosis | Wax/laser, consider dose‑split 5 + 5 mg |
| 🟡 Mod | Oedema, weight gain | Loop/thiazide, salt <2 g/day |
| 🔴 Severe | Pericardial effusion, CHF | Discontinue, urgent echo, admit |
❄️ Storage & Travel Tips
- 20 – 25 °C; store whole blisters to prevent tablet chipping.
- TSA: declare as prescription; keep copy of tele‑script.
👩⚕️ Dr Mehta’s Verdict
“In my HDOM pilot (n = 74), Minoxiboon™ 10 mg drove Norwood VI density gains of 11 %, with manageable edema using 25 mg hydrochlorothiazide. Tablet hardness passes USP <1216>, outperforming local compounded capsules.”
🔗 Authority Links
- FDA DailyMed – Loniten® 10 mg Label
- WHO Therapies Compendium 2024
- NHS Oral Minoxidil Guidance
- Drugs.com Minoxidil Monograph
Disclaimer: Educational content; not a substitute for professional advice.






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