Mirago 50mg

✅ Active Ingredient Overview Table:

🌿 What is Mirabegron 50 mg (Mirago)?

Mirago 50 mg features Mirabegron, a first-in-class β3-adrenoceptor agonist specifically designed to relax detrusor smooth muscle during bladder filling. This targeted mechanism increases bladder capacity and reduces involuntary contractions, delivering significant relief for patients suffering from the disruptive symptoms of OAB.

In clinical studies, the 50 mg dose of Mirabegron has been shown to reduce daily micturition frequency by up to 45% and decrease incontinence episodes by over 50% compared to placebo. Its favorable tolerability profile—lacking anticholinergic adverse effects—makes it an ideal option for those who cannot tolerate or do not respond adequately to muscarinic antagonists.

🧬 Pharmacology & Mechanism of Action

Mirabegron’s selective stimulation of β3 receptors elevates cyclic AMP levels in detrusor muscle cells, relaxing the bladder wall without affecting voiding contractions.

💡 Indications & Dosing

Monitor blood pressure at baseline and periodically; Mirabegron may cause modest increases in systolic blood pressure. Adjust treatment as needed in hypertensive patients.

⚠️ Warnings & Side Effects

Common:

• Hypertension
• Headache
• Nasopharyngitis

Serious:

• Urinary retention
• Arrhythmias (rare)
• Severe hypertension

Use caution in patients with severe uncontrolled hypertension or significant bladder outlet obstruction. Monitor cardiovascular and urinary status regularly.

🏥 Storage Instructions

Store Mirago 50 mg at 20–25°C in original blister packaging. Protect from light and moisture. Keep out of reach of children.

🌐 Availability & Purchasing

• USA: Prescription-only (Myrbetriq); brand and generic ER available.
• UK & EU: Prescription required; generic Mirabegron available.
• Australia: Prescription and TGA approval needed.

Importing from India may reduce cost; confirm regulatory compliance and valid prescription.

🔗 Related OAB Therapies

• Solifenacin 10 mg – M3 antagonist.
• Tolterodine ER 4 mg – antimuscarinic ER.

🎥 Educational Video on Mirabegron

👩‍⚕️ Expert Insight: Dr. Neha Kapoor, Urologist

“Mirago 50 mg provides an effective, non-anticholinergic option for OAB patients, offering significant reductions in urgency and leakage with a favorable safety profile.”