Name: Myotop 450mg
SKU: 22196
Availability: InStock

🔬 Active Ingredient (Generic Name):	Tolperisone Hydrochloride
💊 Indication:	Severe Muscle Spasticity, Chronic Neuromuscular Disorders
🇺🇸 US Brand:	Mylan Tolperisone
🏭 Manufacturer:	Zuventus Healthcare Ltd. (Founded: 1992)
📦 Packaging:	10 Extended-Release Capsules per Strip
🧪 Strength:	450 mg
🚚 Delivery Time:	6 To 15 days

🌿 What is Tolperisone 450 mg (Myotop XL)?

Myotop XL delivers a once-daily 450 mg dose of Tolperisone in an extended-release formulation. It inhibits spinal sodium and calcium channels, enhances microcirculation, and maintains steady plasma concentrations for 24-hour spasticity control in severe cases, such as advanced multiple sclerosis and post-stroke spasticity.

🌍 Availability & Global Brands

Extended-release Tolperisone is marketed under brands like Tolperigo XL. Zuventus’s Myotop XL 450 mg provides consistent dosing and improved adherence, meeting global GMP standards.

🧬 Chemical Composition of Tolperisone

Component	Details
Active Ingredient	Tolperisone Hydrochloride
Chemical Formula	C16H22N2O2
Molecular Weight	270.36 g/mol
Bioavailability	~85%
Metabolism	Hepatic
Half-Life	~2.5 hours (extended-release up to 12 hrs)

💡 Indications & Usage

✅ Severe Spasticity: Indicated for advanced spasticity in neurological disorders requiring continuous symptom relief.

✅ Chronic Control: Extended-release design supports once-daily dosing for stable therapeutic effect.

💊 Dosage Recommendations

Condition	Recommended Dosage
Severe Spasticity	450 mg once daily (morning, with food)

Avoid dose doubling; monitor blood pressure and sedation levels.

🩺 Storage Guidelines

Store Myotop XL 450 mg at room temperature (20°C–25°C).
Protect from moisture and direct sunlight.
Keep out of reach of children.

⚠️ Possible Side Effects

Similar to lower doses, but monitor for increased hypotension, dizziness, and gastrointestinal upset due to higher systemic exposure.

🌐 How to Buy Myotop XL 450 mg in the US, UK, and Australia

Import guidelines mirror the 150 mg formulation, noting the necessity of extended-release import approvals.

🔗 Internal Links to Associated Muscle Relaxants

Liofen 10 mg – Baclofen by Sun Pharma.
Tizan 2 mg – Tizanidine by Sun Pharma.
Myoril 8 mg – Thiocolchicoside by Sanofi India.
Flexura 400 mg – Metaxalone by Sun Pharma.
Pain-O-Soma 500 mg – Carisoprodol by HAB Pharma.

🎥 Educational Video on Extended-Release Tolperisone

👨‍⚕️ Doctor’s Insight: Dr. Asha Kapoor, Neurologist

“Myotop XL 450 mg delivers consistent spasticity control with single daily dosing. It’s crucial to monitor cardiovascular parameters in patients with hypotension risk.”