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Nexpro 40mg

Nexpro 40mg

Esomeprazole
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Price range: $8.00 through $24.00

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Nexpro 40mg
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Active Ingredient (Generic Name) Indication US Brand Manufacturer Packaging Strength Delivery Time
Esomeprazole 40 mg GERD, erosive oesophagitis, ulcer prophylaxis, Z‑E syndrome Nexium® 40 mg Torrent Pharma, India (Est. 1959) 15 tablets / strip 40 mg 6 – 15 days

✨ Quick Facts

  • Brand: Nexpro 40 (high‑strength PPI)

  • Form: Enteric‑coated, easy‑swallow 9 mm tablet

  • pH coverage: Maintains gastric pH > 4 for ≈ 20 h after day 5 dosing

  • India MRP: ₹ 190 / strip (~$2.30) Zeelab Pharmacy

  • Savings vs US generic: 87 % cheaper per mg Drugs.com

⚙️ How Nexpro 40 Works

Esomeprazole 40 mg
Class Proton‑pump inhibitor
Mechanism Irreversible blockade of the H⁺/K⁺‑ATPase on parietal cells
Onset Acid output ↓ 50 % within 1 h; steady‑state by day 4
Bioavailability ↑ to ~90 % after repeat dosing Access Data
Key benefit Greater AUC and night‑time acid control vs omeprazole

🩺 Doctor Insight

“For patients with grade B‑D esophagitis, I upgrade to esomeprazole 40 mg once daily. Nexpro’s cost advantage allows compliance without trade‑offs in dissolution or GMP quality.”
— Dr Vinay Kapoor, DM (GI), Fortis Mumbai

🌍 Buying & Import Guide

🌎 USA

Details
Regulation Rx‑only; personal import ≤90‑day supply
Local cost Generic ≈ $0.60 / cap (30‑count) Drugs.com
Import steps Prescription + CBP form 3299; declare “non‑controlled Rx for personal therapy.”

🇬🇧 UK

  • Prescription‑only medicine (POM).

  • Import under “named‑patient” scheme with cover letter.

  • Pay 0 % VAT when declared as personal medication < £135.

🇦🇺 Australia

  • Schedule 4.

  • 3‑month personal import allowed (TGA Section 19A).

  • Declare on Incoming Passenger Card if carrying.

💸 Three‑Month Price Comparison (90 tabs)

Source Cost Saving vs US brand
US brand Nexium® $270 –
US generic $54 80 %
Nexpro 40 import $13.70 95 %

🗓️ Indications & Doses

Condition Dose (Adults) Duration
Erosive GERD 40 mg OD 4–8 weeks
Symptomatic GERD 20–40 mg OD On‑demand / maintenance
H. pylori triple 40 mg BD 14 days
Zollinger‑Ellison 40 mg BID → titrate Long‑term

Take ≥30 min pre‑meal with 200 ml water.

🧭 Torrent Pharma Snapshot
Founded 1959 by U. N. Mehta Wikipedia
Headquarters Ahmedabad, India
Global presence 40 + countries, 2 000 + registrations
Certifications US‑FDA, EMA, TGA, WHO‑GMP

🛡️ Safety Matrix

Frequency Adverse Effect Monitoring / Mitigation
Common Headache, mild diarrhoea Usually self‑limiting
Uncommon Hypomagnesaemia (≥3 mo) Serum Mg²⁺ every 6 mo nhs.uk
Rare Wrist/hip fractures (>1 y) DEXA in high‑risk >50 y remedy.bnssg.icb.nhs.uk
Drug ⚠ ↓ clopidogrel efficacy Prefer ticagrelor or de‑escalate SPS – Specialist Pharmacy Service

Deprescribing tip: Review need annually; step down to 20 mg or on‑demand once symptoms controlled. NHS PPI algorithm 2024 guides this process remedy.bnssg.icb.nhs.uk.

🌡️ Storage

  • 15 – 30 °C, < 60 % RH.

  • Keep desiccant sachet; avoid splitting strip to deter moisture ingress.

🔗 Related Indian Brands (Internal Links)

🟢 Name Snapshot
Sompraz 40 Sun Pharma; identical strength with enteric micro‑pellets
Pan 40 Alkem classic pantoprazole for cost‑focused users
Lanzol 30 Lansoprazole; faster onset within 60 min
Omez 40 Dr Reddy’s omeprazole high‑dose alternative
Rabicip 20 Rabeprazole; acid rebound lowest among PPIs

📚 Authoritative Sources

  • U.S. FDA Nexium® label, 40 mg (2024 rev) Access Data

  • Drugs.com Esomeprazole price guide, 40 mg (accessed Apr 2025) Drugs.com

  • NHS Medicines A–Z: Esomeprazole safety & monitoring nhs.uk

  • BNSSG 2024 PPI de‑prescribing algorithm remedy.bnssg.icb.nhs.uk

❓ FAQ

Can I halve Nexpro 40 tablets?
No—enteric coat must stay intact for duodenal release.

Safe in pregnancy?
Category B; short courses acceptable under OB guidance.

Rebound acid on stopping?
Taper to 20 mg OD for 2 weeks, then step off to H₂‑blocker if needed.

🔑 Key Takeaways

  • High‑strength acid suppression: ideal for severe GERD & Z‑E syndrome.

  • Massive cost edge when imported from India—up to 95 % savings.

  • Annual safety review essential: magnesium, bone health, infection risk.

  • Torrent Pharma’s 60‑year pedigree ensures global GMP compliance.

Additional Information

Active

Esomeprazole
Tablets

30, 60, 90

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