| Attribute | Details |
|---|---|
| Active Ingredients: | Norfloxacin (400mg) + Tinidazole (600mg) |
| Indication: | Bacterial & Protozoal GI Infections |
| US Availability: | Limited (Import via Intl. Pharmacies) |
| Manufacturer: | Cipla Limited (Est. 1935) |
| Packaging: | Blister packs of 6 or 10 tablets |
| Strength: | 1000mg (Combined) |
| Delivery Time: | 7–14 days (International) |
🌍 Introduction: Norflox TZ’s Dual Mechanism
Norflox TZ 1000mg, a combination drug by Cipla, merges the antibiotic Norfloxacin with the antiprotozoal Tinidazole to treat mixed gastrointestinal infections like traveler’s diarrhea, giardiasis, and amebiasis. This dual-action formula targets both bacteria and parasites, reducing the need for multiple medications. Cipla’s commitment to affordable, high-quality generics makes Norflox TZ a go-to in regions with high infection prevalence.
🔬 Chemical Composition & Mechanism
- Norfloxacin (400mg): Fluoroquinolone antibiotic inhibiting bacterial DNA gyrase.
- Tinidazole (600mg): Nitroimidazole antiprotozoal disrupting DNA synthesis in parasites.
- Excipients: Microcrystalline cellulose, magnesium stearate.
🌐 Global Availability & Pricing
United States
- Status: Not FDA-approved; available via international pharmacies.
- Price: 25–50 per 10-tablet strip.
India
- Brands: Norflox TZ (Cipla), Tridazole-N (Alkem).
- OTC Status: Prescription-only.
- Price: 3–8 per strip.
United Kingdom
- Regulations: Prescription required.
- Price: £15–£35 per pack.
Australia
- TGA Approval: Not listed; consult GP for alternatives.
📊 Price Comparison (Per 10-Tablet Strip)
| Country | Brand | Price (USD) |
|---|---|---|
| USA | Imported | $45 |
| India | Cipla | $5 |
| UK | Generic | $25 |
🏭 Manufacturer Spotlight: Cipla’s Legacy
- Founded: 1935 in Mumbai, India.
- Reputation: Global leader in affordable combination therapies.
- Certifications: WHO-GMP, USFDA-compliant manufacturing.
💊 Dosage & Administration
✅ Adults:
- Acute Infections: 1 tablet twice daily for 5–7 days.
- Chronic Cases: Extended under medical supervision.
⚠️ Contraindications:
- Pregnancy (1st trimester), neurological disorders.
- Alcohol consumption (Tinidazole interaction).
📦 Storage:
- 🌡️ Store below 30°C in a dry place.
- 🔒 Keep away from children.
⚠️ Side Effects & Precautions
| Common | Severe |
|---|---|
| Nausea, Metallic Taste | Peripheral Neuropathy |
| Headache, Dizziness | Seizures (rare) |
🩺 Expert Review: Dr. Arjun Reddy, MD (Gastroenterology)
“Norflox TZ is effective for dual infections, but misuse fuels resistance. Cipla’s formulation is reliable, though patients must avoid alcohol and complete the course.”
🔗 Internal Links to Indian Combination Drugs
- Ciplox TZ: Ciprofloxacin + Tinidazole combo.
📜 Trusted References
❓ FAQs
Q: Can I drink alcohol while taking Norflox TZ?
A: No—Tinidazole causes severe nausea/vomiting with alcohol.
Q: Is a prescription needed in India?
A: Yes, but enforcement varies; consult a pharmacist.
Q: How long does Norflox TZ take to work?
A: Symptoms often improve within 24–48 hours.







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