โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Piroxicam |
|---|---|
| ๐ Indication: | Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Acute Pain |
| ๐บ๐ธ US Brand: | Feldene |
| ๐ญ Manufacturer: | Cipla Limited (Founded: 1935) |
| ๐ฆ Packaging: | 10 Dispersible Tablets per Strip |
| ๐งช Strength: | 20 mg |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What are Piroxicam Dispersible Tablets 20 mg (Pirox DT)?
Pirox DT combines the efficacy of Piroxicam with fast-dissolving technology, providing rapid relief of pain and inflammation. The dispersible tablet dissolves in water or under the tongue, facilitating quick absorption and use in patients with swallowing difficulties.
Clinical studies indicate that Pirox DT achieves peak plasma levels faster than standard capsules, offering significant pain reduction within 30 minutes of administration. This makes it ideal for acute flare-ups of arthritis or rapid management of post-traumatic pain.
Refer to the FDA label for Feldene and the Drugs.com monograph for full prescribing and safety information.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C15H13N3O4S |
| Molecular Weight | 331.35 g/mol |
| Bioavailability | ~100% |
| Metabolism | Hepatic (CYP2C9) |
| Half-Life | ~50 hours |
Piroxicam inhibits COX-1 and COX-2 enzymes, reducing prostaglandin-mediated pain and inflammation.
๐ก Indications & Dosing
| Condition | Dose & Administration |
|---|---|
| Osteoarthritis & Rheumatoid Arthritis | 20 mg once daily; dissolve in a small amount of water and administer after meals |
| Acute Pain Flare-Ups | Single 20 mg dispersible tablet as needed (max 20 mg/day) |
Ensure tablet fully disperses before administration. Do not exceed recommended daily dose.
โ ๏ธ Warnings & Side Effects
Common:
- Gastrointestinal upset (dyspepsia, nausea)
- Headache, dizziness
- Edema
Serious:
- GI bleeding or ulcers
- Cardiovascular risk (MI, stroke)
- Renal impairment
Use lowest effective dose for shortest duration. Monitor GI and cardiovascular status in high-risk patients.
๐ฅ Storage Instructions
Store at 20โ25ยฐC. Keep in original blister to avoid moisture exposure. Avoid high humidity.
๐ Availability & Purchasing
- USA: Prescription-only; limited availability of dispersible formulations.
- UK & EU: Prescription required; dispersible tablets available in some regions.
- Australia: Prescription and TGA approval needed.
Importing from India offers cost savings; ensure prescription and regulatory compliance.
๐ฅ Educational Video on Dispersible NSAIDs
๐จโโ๏ธ Expert Insight: Dr. Meera Singh, Rheumatologist
โDispersible formulations like Pirox DT are game-changers for patients with dysphagia or acute flare-ups, combining rapid onset with dosing convenience.โ




