Rizact

🌿 What is Rizatriptan (Rizact)?

Rizact contains Rizatriptan Benzoate, a selective 5-HT1B/1D receptor agonist indicated for the acute treatment of migraine attacks, whether accompanied by aura or not. It functions by constricting cranial blood vessels and inhibiting the release of inflammatory neuropeptides, thus alleviating pain, light and sound sensitivity, and nausea.

Clinical data reveal that both 5 mg and 10 mg doses provide headache relief within 1–2 hours, with up to 60% of patients pain-free at two hours post-dose. The lower 5 mg dose may be preferred for patients with sensitivity to adverse effects or lower body weight.

For full prescribing and safety details, consult the FDA label for Maxalt, the Drugs.com monograph, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Rizatriptan’s action on 5-HT1B/1D receptors targets migraine pathophysiology by vasoconstriction and decreasing neurogenic inflammation.

💡 Indications & Dosing

Swallow whole with water; do not crush or chew. Adjust dose when used with propranolol.

⚠️ Warnings & Side Effects

Common:

• Dizziness, fatigue
• Paresthesia, dry mouth

Serious (rare):

• Coronary vasospasm (angina, MI)
• Cerebral hemorrhage or ischemic events
• Serotonin syndrome with other serotonergics

Contraindicated in ischemic heart disease, uncontrolled hypertension, and hemiplegic migraine. Monitor cardiovascular status carefully.

🏥 Storage Instructions

Store at 20–25°C in a dry place. Keep tablets in original strip to protect from moisture.

🌐 Availability & Purchasing

• USA: Prescription-only (Maxalt); Rizatriptan generics available.
• UK & EU: Prescription required.
• Australia: Prescription and TGA approval for import.

Importing from India may provide cost savings; ensure compliance with local import regulations and valid prescription.

🔗 Related Migraine Treatments

• Sumatriptan 50/100 mg – Sun Pharma.
• Zolmitriptan 2.5 mg (Zomig) – GSK.
• Eletriptan 40 mg (Relpax) – Pfizer.
• Propranolol 40 mg – prophylaxis.
• Topiramate 100 mg – migraine prevention.

🎥 Educational Video on Rizatriptan

👨‍⚕️ Expert Insight: Dr. Maya Singh, Neurologist

“Rizact’s 5 mg option provides a gentler initiation for patients, while 10 mg delivers robust relief. Timing at headache onset is crucial for optimal efficacy.”