Sumitop

🌿 What is Sumatriptan 100 mg (Sumitop)?

Sumitop contains Sumatriptan Succinate, a selective 5‑HT₁B/₁D receptor agonist used for treating acute migraine attacks with or without aura. It works by constricting dilated cranial blood vessels and inhibiting the release of pro‑inflammatory neuropeptides, thereby reducing headache pain, light sensitivity, sound sensitivity, and nausea.

Clinical trials demonstrate that 100 mg of sumatriptan provides significant pain relief within 60 minutes and sustained freedom from migraine at two hours in a majority of patients. This rapid onset and reliable efficacy help patients return to normal activities sooner.

For detailed prescribing information and safety data, refer to the FDA label for Imitrex, the Drugs.com monograph, the NHS Medicines A–Z entry, and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Sumitriptan’s action at 5‑HT₁B/₁D receptors counteracts migraine pathophysiology by vasoconstriction and neuropeptide inhibition.

💡 Indications & Dosing

Administer Sumitop promptly at migraine onset. Swallow whole with water; do not exceed maximum daily dose.

⚠️ Warnings & Side Effects

Common Adverse Effects:

• Sensations of tightness or pressure in chest, neck, or throat
• Flushing, dizziness
• Drowsiness, fatigue

Serious Risks (rare):

• Coronary artery vasospasm (chest pain, MI)
• Cerebral hemorrhage or ischemic events
• Serotonin syndrome when used with other serotonergic agents

Contraindications include cardiovascular disease, uncontrolled hypertension, and hemiplegic or basilar migraine. Monitor for chest discomfort; discontinue if suspected cardiovascular event.

🏥 Storage Instructions

Store at 20–25°C in original blister packaging. Protect from moisture and light. Keep out of reach of children.

🌐 Availability & Purchasing

• USA: Available by prescription only (Imitrex); generic formulations available in some markets.
• UK & EU: Prescription required; branded and generic versions.
• Australia: Prescription and TGA approval required for import.

Importing from India may offer cost savings; ensure compliance with local regulations and maintain a valid prescription.

🔗 Related Migraine Therapies

• Sumitriptan 50/100 mg (Suminat) – Sun Pharma’s sumatriptan.
• Zolmitriptan 2.5 mg (Zomig) – GlaxoSmithKline.
• Rizatriptan 10 mg (Maxalt) – Merck.
• Eletriptan 40 mg (Relpax) – Pfizer.
• Propranolol 40 mg – migraine prophylaxis.

🎥 Educational Video on Sumatriptan

👨‍⚕️ Expert Commentary: Dr. Maya Singh, Neurologist

“Sumatriptan is a gold standard for acute migraine relief due to its rapid onset and consistent efficacy. Sumitop’s 100 mg tablet offers a reliable, convenient option for patients.”