Mirtazapine

Introduction to Mirtazapine

Mirtazapine is a tetracyclic antidepressant (TeCIA) used primarily to treat major depressive disorder. It works by enhancing serotonin and norepinephrine activity through serotonin receptor antagonism and reuptake inhibition (SARI) . Common brand names include Remeron® , though generics are widely available.

Key Features :

• Active Ingredient : Mirtazapine (chemical formula: C₂₀H₂₆N₄O₂).
• Uses : Depression, insomnia, and off-label use for appetite stimulation.
• Mechanism : Balances neurotransmitters to improve mood and sleep.

Learn more about SSRIs like Escitalopram, which target similar pathways.

Generic Mirtazapine: Cost-Effective Options

Generic Mirtazapine offers significant savings compared to brand-name Remeron® . These generics are chemically identical but cheaper due to reduced R&D costs.

Benefits of Generics :

• Lower prices (e.g., ~$10–$30/month for generics vs. $100+ for brand-name).
• Same efficacy and safety profile.

Indian Manufacturers :

1. Cipla (founded 1935): Produces Mirtazapine 15 mg/30 mg tablets .
2. Sun Pharma (founded 1983): Offers Mirtazapine tablets .
3. Aurobindo Pharma (founded 1976): Provides affordable generic options.

How to Buy Mirtazapine in the US, Australia & UK

US :

• Requires a prescription from a licensed healthcare provider.
• Available at pharmacies like CVS or online via GoodRx (compare prices).

Australia :

• A prescription is mandatory.
• Check Medicare Australia for subsidization options.

UK :

• Prescriptions are issued via NHS or private clinics.
• Purchase at pharmacies like LloydsPharmacy .

Importing from India :

• Ensure compliance with FDA or local regulations (e.g., FDA guidelines for importing medications).
• Use trusted platforms like BuyAllMD to source generics legally.

Indian Manufacturers of Mirtazapine

India is a global leader in generic drug production. Below are key manufacturers and their founding years:

Prices :

• Generics cost ~$0.50–$2 per tablet (varies by dosage).

Mirtazapine Dosage & Storage

Recommended Dosage :

• Starting Dose : 15 mg/day (taken once daily).
• Maximum : 45 mg/day (adjust under medical supervision).

Storage :

• Keep tablets at room temperature (15°C–30°C).
• Avoid moisture and direct sunlight.

Side Effects & Safety Considerations

Common Side Effects :

• Drowsiness, weight gain, dry mouth, dizziness.

Severe Risks :

• Suicidal thoughts (especially in young adults).
• Increased appetite leading to weight gain.

Drug Interactions :

• Avoid MAO inhibitors (e.g., Phenelzine ).

Consult a Doctor :

• Report persistent side effects.
• Learn more about antidepressant interactions via Drugs.com .

Conclusion

Mirtazapine is an effective treatment for depression and insomnia, but its purchase and use require careful planning. Generic options and Indian imports offer cost-effective alternatives, while adherence to dosage guidelines ensures safety. Always consult a healthcare provider before starting treatment.

Explore Related Medications :

• Escitalopram : An SSRI for depression and anxiety.
• Fluoxetine : A long-acting SSRI for mood disorders.
• Sertraline : Used for depression, OCD, and PTSD.

Authoritative Sources

• FDA : Mirtazapine Drug Information .
• Drugs.com : Mirtazapine Side Effects & Dosage .
• NHS : Mirtazapine Guidelines .