✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Carbamazepine
💊 Indication:	Epilepsy (Partial & Generalized Tonic-Clonic Seizures), Trigeminal Neuralgia
🇺🇸 US Brand:	Tegretol
🏭 Manufacturer:	Sun Pharmaceutical Industries Ltd. (Founded: 1993)
📦 Packaging:	10 Tablets per Strip
🧪 Strength:	300 mg
🚚 Delivery Time:	6–15 days

🌿 What is Carbamazepine 300 mg (Zeptol)?

Zeptol 300 mg offers a versatile dose of Carbamazepine, an anticonvulsant that modulates voltage-gated sodium channels, decreasing neuronal hyperexcitability. This dosage is suited for patients requiring moderate seizure control or maintenance therapy.

Clinical trials show that dividing 300 mg into twice-daily dosing maintains steady plasma levels, reduces seizure frequency by up to 50%, and alleviates trigeminal neuralgia pain when titrated appropriately.

For prescribing information and safety details, consult the FDA label for Tegretol and the Drugs.com monograph. The NHS Medicines A–Z entry and the WHO Essential Medicines List provide additional guidance.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C15H12N2O
Molecular Weight	236.27 g/mol
Bioavailability	~75%
Metabolism	Hepatic (CYP3A4)
Half-Life	12–17 hours

Carbamazepine stabilizes hyperexcited neuronal membranes and interrupts repetitive firing by inhibiting sodium channels.

💡 Indications & Dosing

Condition	Dose & Titration
Partial & Generalized Tonic-Clonic Seizures	300 mg twice daily; adjust weekly by 100–200 mg to target 800–1,200 mg/day
Trigeminal Neuralgia	100 mg three times daily; titrate to 300 mg twice daily as needed

Take with food to reduce gastrointestinal upset. Monitor plasma levels where available due to non-linear kinetics.

⚠️ Warnings & Side Effects

Common:

Drowsiness, dizziness
Nausea, ataxia
Hyponatremia

Serious:

SJS/TEN risk (HLA-B*1502 in Asians)
Blood dyscrasias (agranulocytosis, aplastic anemia)
Hepatotoxicity

Screen for HLA-B*1502 in at-risk groups. Regularly monitor CBC, LFTs, and sodium levels. Discontinue at first sign of rash.

🏥 Storage Instructions

Store Zeptol 300 mg at 20–25°C in its original blister pack. Protect from moisture and light. Keep out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only; generic carbamazepine available.
UK & EU: Prescription required; widely accessible generics.
Australia: Prescription needed; TGA-approved.

Importing from India may reduce costs; ensure regulatory compliance and maintain a valid prescription.

🔗 Related Antiepileptic Drugs

Lamotrigine 100 mg – adjunctive mood stabilizer.

🎥 Educational Video on Carbamazepine

👩‍⚕️ Expert Insight: Dr. Neeta Sharma, Neurologist

“A 300 mg divided regimen balances efficacy and tolerability. Monitoring HLA-B*1502 and routine labs is essential to prevent severe reactions and ensure safe long-term use.”