✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Diclofenac Diethylamine 1.16%
💊 Indication:	Topical relief for localized musculoskeletal pain (deep tissue)
🇺🇸 US Brand:	Voltaren TPM Gel
🏭 Manufacturer:	Novartis India Ltd (Founded: 1997)
📦 Packaging:	30 g Tube
🧪 Strength:	1.16% (11.6 mg/g) Diclofenac DEA
🚚 Delivery Time:	6–15 days

🌿 What is Diclofenac Diethylamine 1.16% TPM Gel (Voveran TPM Gel)?

Voveran TPM Gel uses transdermal penetration enhancer technology in a gel base to deliver Diclofenac Diethylamine deep into inflamed tissues. The gel targets pain in muscles, ligaments, and joints more effectively than standard topical formulations, providing sustained anti-inflammatory and analgesic action without systemic side effects.

For prescribing and safety information, consult the Drugs.com topical diclofenac guide, the NHS Medicines A–Z entry, and the WHO Model List of Essential Medicines.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C14H10Cl2NO2•C8H19N (salt)
Molecular Weight	Approx. 334.22 g/mol (salt)
Permeation	Enhanced via transdermal penetration matrix
Metabolism	Minimal systemic absorption; hepatic if absorbed
Duration of Effect	Up to 12 hours per application

The TPM gel matrix facilitates increased diclofenac delivery to deep tissues, enhancing COX inhibition and reducing inflammatory mediators locally.

💡 Indications & Application

Deep Muscular Pain: Apply a thin layer over the affected area twice daily.
Ligament & Tendon Injuries: Massage gel 2–3 cm longitudinally along tendon insertion sites.
Joint Pain (Knee, Shoulder): Use for up to 14 days; monitor skin tolerance.

Wash hands before and after use. Do not apply to broken skin or open wounds. Avoid occlusive dressings.

⚠️ Warnings & Side Effects

Common (Local):

Skin redness
Mild burning or stinging sensation

Serious (Rare):

Contact dermatitis
Photosensitivity reactions

Discontinue use if severe skin reactions occur. Limit sun exposure on treated area and protect with clothing.

🏥 Storage Instructions

Store TPM Gel at 20–25°C. Keep tube tightly closed. Protect from light and moisture. Keep out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only topical diclofenac gels.
UK & EU: OTC and prescription topical diclofenac.
Australia: OTC for musculoskeletal pain.

Importing from India may reduce cost; ensure regulatory compliance and maintain valid prescription if required.

🔗 Related Topical Analgesics

Voveran Emulgel 1.16% – standard topical gel.
Fastum Gel 2.5% – ketoprofen.
Ketorol Gel 4% – ketorolac.

🎥 Educational Video on TPM Gel Technology

👩‍⚕️ Expert Insight: Dr. Rakesh Jain, Rheumatologist

“TPM Gel technology enhances diclofenac delivery to deep-seated tissues, offering superior relief in conditions like tendonitis and deep muscle strains compared to regular topical gels.”