โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Benzoyl Peroxide |
|---|---|
| ๐ Indication: | Acne Vulgaris (Comedonal & Inflammatory Lesions) |
| ๐บ๐ธ US Brand Equivalent: | Clearasil, PanOxyl |
| ๐ญ Manufacturer: | Wallace Pharmaceuticals Pvt. Ltd. (Founded: 1977) |
| ๐ฆ Packaging: | 30 g Tube |
| ๐งช Strength: | 2.5% w/w |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What is Benzoyl Peroxide 2.5% Gel (Persol AC)?
Persol AC 2.5% Gel offers a milder formulation of benzoyl peroxide, ideal for individuals with sensitive skin or those new to acne therapy. Benzoyl peroxide works by releasing free radicals, delivering oxygen into pores to eliminate Propionibacterium acnes, while its mild keratolytic effect promotes gentle exfoliation of follicular keratinocytes.
Mild to moderate acne patients often experience irritation or dryness with higher concentrations. Persol ACโs 2.5% strength balances efficacy and tolerability, reducing lesion counts and inflammation over 6โ8 weeks of consistent use. The lightweight gel base ensures rapid absorption without a greasy residue, making it suitable for combination with other topical therapies.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C14H10O4 |
| Molecular Weight | 242.23 g/mol |
| Mode of Action | Releases free radicals โ oxidizes bacterial cell walls; mild keratolytic by softening and shedding stratum corneum cells |
| Antibacterial Spectrum | Primarily targets P. acnes and some anaerobic bacteria |
๐ก Indications & Application Guidelines
| Condition | Application |
|---|---|
| Acne Vulgaris | โข Cleanse and dry affected areas. |
| โข Apply a thin layer of Persol AC Gel 2.5% once nightly to acne-prone regions. | |
| โข If tolerated, increase to twice daily (morning & evening). | |
| โข Continue for at least 6โ8 weeks to evaluate improvement. |
Avoid contact with eyes, lips, and mucous membranes. Use a gentle non-comedogenic moisturizer if dryness occurs. Discontinue if severe irritation develops.
โ ๏ธ Warnings & Side Effects
Common:
- Mild dryness, peeling, scaling
- Transient stinging or burning sensation
Less Common:
- Contact dermatitis
- Erythema (redness) at application site
Precautions:
- Perform a patch test before widespread use if prone to sensitivity.
- Use sunscreen daily; benzoyl peroxide may increase photosensitivity.
- Avoid contact with dyed fabrics, hair, or colored textiles to prevent bleaching.
Discontinue if severe irritation or allergic reaction occurs and consult a dermatologist.
๐ฅ Storage Instructions
Store Persol AC Gel 2.5% at 20โ25ยฐC in its original tube. Protect from heat and direct sunlight. Ensure the cap is tightly closed between uses. Keep out of reach of children and pets.
๐ Availability & Purchasing
- United States: OTC benzoyl peroxide gels (2.5%โ10%) widely available; consult a healthcare provider for 2.5% recommendations.
- United Kingdom & EU: Available OTC in various strengths; Persol AC can be imported with a valid prescription.
- Australia: OTC benzoyl peroxide products are accessible; 2.5% formulations available through pharmacist advice.
Persol AC 2.5% Gel from India provides an affordable acne management option. Adhere to local import regulations and maintain prescription or pharmacist recommendations.
๐Links to Authoritative Resources
๐ Topical Therapies (Indian Brands)
- Clindac A Gel โ Clindamycin Phosphate 1% gel for inflammatory acne.
- Adapen Gel โ Adapalene 0.1% gel for comedonal lesions and maintenance.
- Aziderm 10% Gel โ Azelaic Acid 10% gel for acne and rosacea.
๐ฅ Educational Video on Acne Management
๐จโโ๏ธ Expert Insight: Dr. Anjali Mehta, Dermatologist
โLower-strength benzoyl peroxide, such as 2.5%, helps minimize irritation while still offering effective antibacterial and keratolytic effects. Persol AC 2.5% Gel is an excellent starting point for sensitive skin types.โ




