✅ Active Ingredient Overview Table:

🔬 Active Ingredients:	Betamethasone Valerate 0.1% w/w, Clioquinol 3% w/w
💊 Indication:	Infected Dermatoses, Eczematous Dermatitis with Secondary Bacterial/Fungal Infection
🇺🇸 US Brand Equivalent:	N/A (Comparable components: Diprolene for Betamethasone, Vioform for Clioquinol)
🏭 Manufacturer:	GlaxoSmithKline Pharmaceuticals Ltd (Founded: 2000)
📦 Packaging:	30 g Tube
🧪 Strengths:	Betamethasone Valerate 0.1% w/wClioquinol 3% w/w
🚚 Delivery Time:	6–15 days

🌿 What Is Betnovate C Ointment?

Betnovate C combines a potent topical corticosteroid (Betamethasone Valerate 0.1%) with Clioquinol 3%, an antibacterial and antifungal agent. This combination is indicated for inflammatory dermatoses complicated by secondary bacterial or fungal infection, such as impetiginized eczema, intertrigo, and infected psoriasis. Betamethasone reduces inflammation, itching, and erythema, while Clioquinol targets superficial Gram-positive bacteria (e.g., Staphylococcus aureus) and dermatophytes, hastening resolution of infection and preventing spread.

🧬 Pharmacology & Mechanism of Action

Component	Mechanism
Betamethasone Valerate 0.1%	• Binds glucocorticoid receptors → downregulates pro-inflammatory cytokines (IL‑1, TNF‑α) • Inhibits leukocyte infiltration and histamine release → reduces pruritus and erythema
Clioquinol 3%	• Chelates metal ions in bacterial/fungal enzymes → disrupts membrane permeability, impairing DNA synthesis • Effective against Gram‑positive cocci and dermatophytes
Ointment Base	• Provides occlusion → enhances skin penetration of actives and maintains moist environment for healing

💡 Indications & Application Guidelines

Condition	Application Regimen
Impetiginized Eczema / Intertrigo with Infection	• Gently cleanse and pat dry the affected area. • Apply a thin layer of Betnovate C Ointment 1–2 times daily until infection resolves (usually 7–10 days). • Discontinue Clioquinol component after 7 days; continue Betamethasone mono‑therapy if inflammation persists (max 14 days total).
Infected Psoriatic Lesions	• Cleanse area; apply Betnovate C to plaques with surrounding erythema twice daily. • Use for up to 7 days; switch to topical steroid alone thereafter.
Bacterial/Fungal Superinfection (e.g., Tinea, Candidal)	• Cleanse and dry; apply thin layer twice daily for 7–10 days. • Monitor for resolution; if fungal elements persist, consider systemic therapy or fungal‑specific topical after initial control with Betnovate C.

Avoid application to face, groin, and axilla unless directed. Do not bandage or occlude unless under specialist supervision. Discontinue if severe irritation or hypersensitivity occurs.

⚠️ Warnings & Side Effects

Common:

Local burning or stinging upon application
Dryness or peeling in sensitive areas
Mild folliculitis

Less Common:

Contact dermatitis (allergic)
Hypopigmentation or hypertrichosis with prolonged steroid use

Serious (Rare):

Secondary fungal overgrowth (e.g., Candida) if used beyond recommended duration
HPA axis suppression (with extensive or occluded use)
Telangiectasia or skin atrophy in treated area

Precautions:

Limit Betamethasone use to 14 days in body, 7 days in intertriginous areas.
Use Clioquinol component only for 7–10 days to reduce resistance risk and mucosal irritation.
Avoid in children under 2 years unless under pediatric dermatologist supervision.
Do not apply to deep puncture wounds, animal bites, or uncleaned burn areas.

Inform patients to report signs of hypersensitivity (rash, swelling, severe itching) immediately and to use sunscreen if applied to sun‑exposed areas.

🏥 Storage Instructions

Store Betnovate C Ointment at 20–25°C in its original tube. Protect from direct sunlight and moisture. Replace cap securely after each use. Keep out of reach of children and pets.

🌐 Availability & Purchasing

United States: No direct branded Betnovate C; components available separately by prescription (e.g., Diprolene & clioquinol formulations). Combination compounding possible in specialized pharmacies under physician order.
United Kingdom & EU: Betnovate C prescribed by dermatologists; combination topical corticosteroid/antibiotic preparations are prescription‑only.
Australia: Betnovate C available under PBS; prescription required for infected dermatoses.

Importing Betnovate C from India must comply with personal importation regulations; ensure a valid prescription and complete customs documentation to avoid delays.

🔗 Authoritative Resources

🔗 Related Topical Therapies (Indian Brands)

Betnovate Ointment – Betamethasone Valerate 0.1% for inflammatory dermatoses.

🎥 Educational Video on Combination Therapies for Infected Dermatitis

👩‍⚕️ Expert Insight: Dr. Ramesh Patel, Dermatologist

“Betnovate C Ointment addresses both inflammation and secondary infection in one formulation. Its combined action shortens healing time, reduces scarring, and prevents recurrence in impetiginized eczema and other infected dermatoses.”