📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Active Ingredient	Isotretinoin
🧪 Strengths Available	5mg, 10mg, 20mg, 25mg, 30mg
🏭 Manufacturer	Intas Pharmaceuticals Ltd.
💊 Form	Soft Gelatin Capsule
📦 Packaging	10 capsules per strip
🩺 Indication	Severe acne (nodulocystic, recalcitrant), acne vulgaris
⏱️ Delivery Time	6 to 15 days

🧬 What is Tretiva Soft Capsule (Isotretinoin) Used For?

Tretiva Soft Capsules, manufactured by Intas Pharmaceuticals Ltd., are oral formulations of Isotretinoin, a potent derivative of Vitamin A. This retinoid is primarily prescribed for the treatment of severe, resistant acne that hasn’t responded to topical treatments or antibiotics.

Isotretinoin works by reducing sebaceous gland size, suppressing oil (sebum) production, preventing clogging of skin pores, and possessing anti-inflammatory effects. The various strengths (5mg, 10mg, 20mg, 25mg, 30mg) allow for customized dosing based on patient weight, response, and tolerance.

Tretiva has shown remarkable success in permanently reducing acne lesions and improving long-term skin clarity.

🎥 Video Section: Safe Use of Tretiva (Isotretinoin)

📺 “Oral Isotretinoin: Dermatologist Dos and Don’ts“

🎬 Video Placeholder — Covers safe dosing, pregnancy risks, dietary tips, and monitoring requirements during Isotretinoin therapy.

Caution: Always take under dermatological supervision due to serious side effect risks.

🩺 Indications for Use

Severe nodular acne
Recalcitrant acne vulgaris
Acne not responsive to antibiotics
Persistent cystic or scarring acne

💡 Dosage & Administration Guide

💊 Strength	⚖️ Body Weight-Based Dose	🧴 Usage Instructions
5mg	For very low body weight or high sensitivity	Take once daily with food; adjust as needed
10mg	Initiation or mild tolerance	Once or twice daily, based on acne severity
20mg	Moderate acne cases	Standard maintenance dose
25mg	Heavier patients needing stronger dosage	As directed by physician
30mg	Advanced acne management	May be split into two doses per day

Treatment duration typically lasts 16–24 weeks. Regular blood tests are recommended.

⚠️ Warnings & Side Effects

💥 Common Effects	❗ Serious Risks
Dry lips, dry skin, nosebleeds	Liver enzyme changes, depression, birth defects (teratogenic)
Sensitivity to sunlight	Vision changes, pancreatitis, bone pain
Muscle aches	Severe allergic reactions (rare)

⚠️ Pregnancy Warning: Isotretinoin is highly teratogenic. Do not use during pregnancy. Women must use two forms of contraception during and one month after treatment.

🧃 Storage Guidelines

Store at room temperature below 25°C
Keep away from moisture and direct sunlight
Do not crush or chew capsules
Keep out of reach of children

🌍 Availability & Ordering Info

🌎 Country	📦 Import Allowed	📋 Prescription Needed
🇺🇸 USA	Yes (via FDA personal import)	Yes
🇬🇧 UK	Yes (under MHRA guidelines)	Yes
🇦🇺 Australia	Yes (TGA personal import scheme)	Yes

🔗 Related Products (Internal Links)

💊 Product	🏭 Manufacturer	📖 Brief Description
Accufine Soft Capsule	Healing Pharma	Alternative isotretinoin brand for severe nodular acne
Isotroin Capsule	Cipla Ltd.	Popular Indian isotretinoin product for cystic acne treatment
Retino-A Cream 0.05%	Johnson & Johnson	Topical tretinoin cream for milder acne and maintenance after isotretinoin
Tretiva 20mg Capsule	Intas Pharmaceuticals	Single strength version often used in high-dose therapy
Tretinoin Gel USP 0.1%	Sun Pharma	Topical retinoid used post-oral therapy to maintain clear skin

📚 External Medical References

FDA – Isotretinoin Guide
Drugs.com – Isotretinoin
NHS – Acne Treatment Options
PubMed – Isotretinoin Research
AAD – Oral Retinoid Therapy

🩺 Expert Review – Dr. Kavita Menon, MD Dermatology

“Isotretinoin, when monitored properly, is a revolutionary option for acne that doesn’t respond to conventional treatments. Tretiva by Intas is widely used in India and internationally due to its consistent efficacy and tolerability.”

⚠️ Disclaimer

This article is for informational purposes only. Tretiva (Isotretinoin) should only be taken under the supervision of a certified healthcare provider. Follow all local import and prescription guidelines.