📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Active Ingredients	Naltrexone Hydrochloride 8mg + Bupropion Hydrochloride 90mg
🧪 Formulation	Fixed-dose combination (FDC) tablet
🏭 Manufacturer	Kachhela Medex Pvt. Ltd.
💊 Dosage Form	Oral Tablet
📦 Packaging	10 tablets per strip
🩺 Indication	Weight Management in Obese or Overweight Adults
🇺🇸 US Brand Equivalent	Contrave (by Currax Pharmaceuticals)
⏱️ Delivery Time	6 to 15 days

🧬 Introduction – What is Lodonak BP?

Lodonak BP is a dual-acting pharmaceutical developed by Kachhela Medex Pvt. Ltd. that contains Naltrexone 8mg and Bupropion 90mg. It mimics the formulation of the US FDA-approved brand Contrave, and is primarily used as part of a comprehensive weight-loss plan.

This fixed-dose combination works through two synergistic mechanisms: Naltrexone affects opioid receptors to reduce food cravings, while Bupropion, an atypical antidepressant, stimulates the hypothalamus to suppress appetite and boost energy expenditure. Lodonak BP is suited for adults with a BMI ≥30, or BMI ≥27 with risk factors like diabetes or high cholesterol.

🎥 Video Overview – Dual Action Weight Loss Support

📺 “How Naltrexone + Bupropion Combos Like Lodonak BP Aid in Weight Loss“

🎬 Video Placeholder – Covers how Lodonak BP affects appetite control and metabolic pathways.

Always use under a doctor’s guidance. This is not an over-the-counter supplement.

🔬 Mechanism of Action

🧪 Ingredient	🎯 Primary Function
Naltrexone 8mg	Opioid antagonist; reduces cravings and food reward response
Bupropion 90mg	Dopamine/norepinephrine reuptake inhibitor; suppresses appetite and boosts energy

These two compounds act on the hypothalamic hunger center and reward systems, helping reduce emotional eating and promote better adherence to a low-calorie diet.

💡 Dosage Guidelines (As Prescribed)

📆 Week	💊 Dosage (Per Day)
Week 1	1 tablet in the morning
Week 2	1 tablet in the morning, 1 tablet in the evening
Week 3+	2 tablets per day (as prescribed)

Treatment duration depends on patient progress and physician evaluation.

⚠️ Side Effects & Safety Information

💥 Common Side Effects	❗ Serious Risks (Rare)
Nausea, constipation	Increased blood pressure
Insomnia, dry mouth	Seizures (especially with high doses)
Headache, dizziness	Suicidal thoughts in patients with depression

Contraindications: Epilepsy, eating disorders, uncontrolled hypertension, opioid dependence.

🧃 Storage & Handling

Store below 30°C in a dry place
Keep out of reach of children
Protect from direct sunlight and moisture

🌍 Global Availability & Import Notes

🌎 Region	📦 Import Policy	📋 Prescription Requirement
🇺🇸 USA	Personal import allowed for equivalents	Yes
🇬🇧 UK	Import for personal use with prescription	Yes
🇦🇺 Australia	Requires valid prescription and TGA approval	Yes

🔗 Related Products (Internal Links)

💊 Product Name	🏭 Manufacturer	📖 Description
Contraburn 8/90mg	Kachhela Medex Pvt. Ltd.	Another Naltrexone/Bupropion combo used for weight management
Obelit 120mg	Intas Pharmaceuticals Ltd	Orlistat capsule that blocks fat absorption
Slimtop 120mg	Healing Pharma	Weight-loss aid containing Orlistat
AyurSlim 60 Tablets	Himalaya Drug Company	Herbal weight management supplement
Reeshape 120mg	Meyer Organics	Alternative Orlistat formulation for obesity treatment

📚 Scientific & Medical References

🩺 Expert Insight – Dr. Mira Kapoor, MD (Metabolic Medicine)

“Combining naltrexone with bupropion offers a unique dual mechanism: appetite regulation and craving control. While highly effective for committed patients, Lodonak BP must be prescribed cautiously, especially in patients with hypertension or mood disorders.”

⚠️ Disclaimer

This article is for informational use only and does not replace professional medical advice. Lodonak BP should only be used under medical supervision. Availability and legality vary by country.