📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Product Name	Premarin Vaginal Cream
🧬 Active Ingredient	Conjugated Estrogens
🏭 Manufacturer	Wyeth Pfizer Ltd
💡 Indication	Vaginal atrophy, dryness, irritation, postmenopausal discomfort
📦 Packaging	14 gm tube with applicator
🌍 Country of Origin	India
⏱️ Delivery Time	6 to 15 business days

🧬 Introduction – What is Premarin Vaginal Cream?

Premarin Vaginal Cream is a topical hormone replacement treatment developed by Wyeth Pfizer Ltd, containing conjugated estrogens. It is primarily used to relieve symptoms associated with vaginal atrophy due to estrogen deficiency in postmenopausal women. These symptoms include vaginal dryness, itching, burning, and painful intercourse (dyspareunia).

Applied intravaginally using a specially designed applicator, Premarin delivers estrogen directly to the affected tissues, promoting healing, elasticity, and hydration. Unlike systemic estrogen therapy, this local application minimizes systemic absorption and reduces associated risks.

Premarin Vaginal Cream is considered a gold standard in treating localized menopausal symptoms and is often preferred by women seeking non-oral therapy.

🎥 Educational Video Overview

📺 “Topical Estrogen Therapy for Vaginal Atrophy – Is It Right for You?“
🎬 Video Placeholder – Overview of conjugated estrogen creams, application techniques, and safety.

🎙️ Featuring gynecologist Dr. Anita Khurana, MD

🔬 Mechanism of Action – How It Works

⚗️ Effect	🔍 Mechanism
Tissue rejuvenation	Replenishes estrogen in vaginal tissues to restore elasticity and tone
Lubrication enhancement	Increases mucosal secretions to reduce dryness
Symptom relief	Reduces burning, pain, and discomfort associated with atrophy

💊 Indications & Dosage Guidelines

🩺 Condition	💉 Recommended Use
Vaginal dryness, burning, itching	0.5 to 1 gram intravaginally daily for 1–2 weeks
Dyspareunia	Maintenance dose: 0.5 to 1 gram twice per week

Note: Use the applicator provided and follow your doctor’s dosage instructions. Do not exceed recommended duration without review.

⚠️ Side Effects & Precautions

💥 Common Side Effects	❗ Serious Reactions
Vaginal discharge	Risk of endometrial hyperplasia (if overused)
Breast tenderness	Rare systemic effects like thromboembolism (minimal via vaginal route)
Headache or nausea	Vaginal bleeding (report immediately)

Premarin Cream is generally safe for short-term localized use. Periodic monitoring may be needed for long-term therapy.

🧃 Storage Instructions

Store at temperatures between 15–30°C
Do not freeze
Replace cap tightly after use
Keep out of reach of children

🌍 Global Availability & Import Guidelines

🌎 Region	🚚 Import Notes	📜 Prescription Required
🇺🇸 USA	FDA permits personal importation with a valid prescription	✅ Yes
🇬🇧 UK	MHRA allows for personal import for therapy use	✅ Yes
🇦🇺 Australia	TGA permits import with prescription under personal scheme	✅ Yes

Typical Delivery Time: 6–15 business days.

🔗 Related Products (Internal Links)

💊 Product	🏭 Manufacturer	📖 Description
Estrabet Gel	Abbott India Pvt Ltd	Topical estrogen gel for menopausal symptom relief
Oestrogel	Besins Healthcare	Transdermal estrogen therapy for systemic use
Progynova 2 mg	Zydus Healthcare	Oral estradiol tablet used in hormone therapy
Evadiol 2 mg	Intas Pharmaceuticals	Alternative oral HRT formulation
Estraval Depot	Actiza Pharmaceutical	Long-acting injectable estrogen treatment

📚 References & External Resources

🩺 Doctor’s Commentary – Dr. Anita Khurana, MD (Gynecology)

“Premarin Vaginal Cream offers women a focused and effective way to manage vaginal discomfort during menopause. When used as prescribed, it provides localized symptom control without major systemic risks.”

⚠️ Disclaimer

This article is for educational purposes only. Premarin Vaginal Cream should be used under the direction of a licensed medical provider. Consult your doctor before starting treatment.