📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Product Name	Duvadilan 10 mg Tablets
🧬 Active Ingredient	Isoxsuprine Hydrochloride
🏭 Manufacturer	Abbott India Pvt. Ltd.
💡 Indication	Uterine relaxant for preterm labor
🇺🇸 US Brand	Vasodilan
📦 Packaging	50 tablets per strip
🌍 Country of Origin	India
⏱️ Delivery Time	6 to 15 business days

🧬 Introduction – What is Duvadilan?

Duvadilan 10 mg contains isoxsuprine HCl, a tocolytic agent used to relax uterine smooth muscle, thereby delaying preterm labor. Manufactured by Abbott India, it’s often prescribed in OB-GYN practice to help prolong pregnancy and reduce the risk of premature birth.

As a β₂-adrenergic agonist, isoxsuprine reduces uterine contractions and improves uterine blood flow. Accent is placed on balancing timing and dosing to optimize fetal outcomes.

🎥 Educational Video Overview

📺 “Tocolysis: Preventing Preterm Labor with Tocolytics”
🎬 Video Placeholder – Covers indications, mechanism, dosing, and pregnancy monitoring.

💬 Reviewed by: Dr. Rekha Sharma, MD (Obstetrics & Maternal-Fetal Medicine)

🔬 Mechanism of Action

🎯 Action	💡 Physiological Effect
β₂‑agonist activity	Relaxes uterine muscle by lowering intracellular Ca²⁺
Vasodilation	Improves uteroplacental blood flow
Uterine relaxation	Reduces frequency and intensity of contractions

💊 Indications & Dosage Guidelines

🩺 Condition	💊 Recommended Dose
Preterm labor prevention	10 mg orally 3–4 times daily, per medical advice
Raynaud’s phenomenon*	Off‑label: 10 mg TID for vascular blood flow support

*Always follow physician instructions—this is limited and not primary indication.

⚠️ Side Effects & Precautions

🔸 Common Side Effects	🔸 Potential Serious Effects
Flushing, headache	Tachycardia, hypotension
Nausea, dizziness	Pulmonary edema (rare)
Palpitations	Hypertensive reactions in predisposed patients

⚠️ Use with caution in cardiac patients; contraindicated in hypertension, hyperthyroidism, and severe cardiovascular disease.

🧃 Storage & Handling

Store at 20–25 °C (room temperature)
Keep in original blister strip
Protect from light and moisture
Keep out of children’s reach

🌍 Global Availability & Import Guidance

🌎 Region	🚚 Import Notes	📜 Rx Required
🇺🇸 USA	Not FDA-approved; import under personal use policy	✅ Yes
🇬🇧 UK	Permitted under MHRA personal medical exemption	✅ Yes
🇦🇺 Australia	Allowed with TGA personal import with prescription	✅ Yes

Typical delivery: 6–15 business days, depending on location and courier.

📚 References & External Resources

🩺 Expert Commentary – Dr. Rekha Sharma, MD

“Isoxsuprine, though an older tocolytic, still plays a role in extending gestational age by relaxing uterine muscles. When used judiciously, Duvadilan offers a practical adjunct in managing threatened preterm labor.”

⚠️ Disclaimer

This article is for informational purposes only. Duvadilan 10 mg (Isoxsuprine) should be used under strict medical supervision. Consult your doctor before use.