| ๐ท๏ธย Parameter | ๐ย Details |
|---|---|
| ๐งฌ Active Ingredient | Oxcarbazepine |
| ๐ Indication | Partial Seizures, Bipolar Disorder (off-label) |
| ๐บ๐ธ US Brand | Trileptalยฎ |
| ๐ญ Manufacturer | Cipla Ltd. |
| ๐ฆ Packaging | Blister strips of 10 tablets (150mg, 300mg, 600mg) |
| ๐ช Strength | 150 mg, 300 mg, 600 mg |
| ๐ Delivery Time | 7โ14 days (Worldwide) |
๐ง Introduction to Oxcarb (Oxcarbazepine)
Oxcarb by Cipla containsย Oxcarbazepine, a ketone-derivative antiepileptic drug metabolized to activeย eslicarbazepine. It stabilizes hyperexcitable neurons by blocking voltage-sensitive sodium channels, approved for:
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โกย Partial seizuresย (monotherapy/adjuvant in adults & children โฅ6 years)
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๐ย Bipolar disorderย (off-label mood stabilizer at 600โ1200 mg/day)
Advantages over carbamazepine: lower risk of severe rash and no auto-induction of metabolism. Cipla’s formulation offers cost-effective seizure control.
๐ Dosage & Indications
| ๐ย Indication | ๐งชย Dosage | โฑ๏ธย Frequency | ๐กย Route |
|---|---|---|---|
| Adults: Partial Seizures | Start 300 mg BID โ Max 2400 mg/day | Twice daily | Oral |
| Children (6โ17y): Seizures | 8โ10 mg/kg/day โ Max 900 mg/day | Twice daily | Oral |
| Bipolar (Off-label) | 600โ1200 mg/day | Twice daily | Oral |
| Elderly/Renal Impairment | Reduce dose by 25% if CrCl <30 mL/min | Twice daily | Oral |
โ ๏ธ Side Effects, Storage & Warnings
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โ Common Side Effects: Dizziness (32%), diplopia (16%), fatigue, hyponatremia (low sodium).
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๐ซ Serious Effects:
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Stevens-Johnson syndrome (SJS) in HLA-B*1502 carriers
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Suicidal ideation (monitor mood changes)
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Severe hyponatremia (Na+ <125 mmol/L)
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โ๏ธ Storage: Below 30ยฐC; protect from moisture (keep in original blister).
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โ ๏ธ Warnings:
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Test HLA-B*1502 allele in Asian patients before use.
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Monitor serum sodium monthly for first 3 months.
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Avoid in AV heart block or severe hepatic impairment.
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๐ Global Availability & Shipping
| ๐ย Region | ๐ฆย Shipping | ๐ตย Price (300mg pack) | ๐ย Prescription |
|---|---|---|---|
| ๐บ๐ธ USA | โ Yes | $35โ$55 | Required |
| ๐ฌ๐ง UK | โ Yes | ยฃ30โยฃ45 | Required |
| ๐ฆ๐บ Australia | โ Yes | AUD 50โ80 | Required |
๐ Related Indian Alternatives (Different in Same Category)
| ๐ Product Name | ๐ญ Manufacturer | ๐ Internal Link |
|---|---|---|
| Trileptal (Oxcarbazepine) | Novartis | Trileptal |
| Tegrital (Carbamazepine) | Cipla | Tegrital |
| Keppra (Levetiracetam) | Sun Pharma | Keppra |
| Eptoin (Phenytoin) | Abbott | Eptoin |
| Valparin (Sodium Valproate) | Sanofi | Valparin |
| Gabantin (Gabapentin) | Sun Pharma | Gabantin |
๐ External Medical References
๐ฉบ Expert Commentary
Dr. Ananya Reddy, Neurologist:
“Oxcarb is first-line for new-onset focal seizures due to its tolerability. For patients with sodium concerns, [Keppra] (Levetiracetam) is safer. Always screen HLA-B1502 in Southeast Asian populations โ Ciplaโs Oxcarb carries the same risk as branded Trileptal.”*
๐ Disclaimer
This information is for educational purposes. Consult a neurologist before use. Ciplaโs Oxcarb is not FDA-approved for bipolar disorder.
๐ก Clinical Tips:
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Hyponatremia Prevention: Limit fluid intake to 1.5L/day; check baseline sodium.
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Switching from Carbamazepine: Replace with 1.5ร Oxcarb dose (e.g., 400mg carbamazepine โ 600mg Oxcarb).
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Cipla Tablet ID:
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150mg: “CIPLA” over “147”
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300mg: “CIPLA” over “148”
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600mg: “CIPLA” over “149”
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Missed Dose: Take immediately if <6 hours late; otherwise skip to avoid dizziness.




