Alcoliv 500mg

Metadoxine • 10 Tablets per Blister by Sun Pharma

Pharmaceutical-grade hepatoprotective and detoxifying agent by Sun Pharmaceutical Industries Ltd •
Accelerates ethanol and acetaldehyde clearance • Protects liver cells • Supports recovery in alcoholic liver disease, fatty liver, and elevated liver enzymes

💊 ALCOLIV (METADOXINE) BY SUN PHARMA

🏭

Manufactured by Sun Pharmaceutical Industries Ltd

Sun Pharma is the world’s fourth largest specialty generic pharmaceutical company and India’s top pharma manufacturer.
Alcoliv (Metadoxine 500mg) combines pyridoxine (Vitamin B6) and pyrrolidone carboxylate (PCA) to accelerate ethanol metabolism,
reduce acetaldehyde toxicity, and support hepatic regeneration. Trusted quality for liver health management.

📦 Product Specifications

Generic Name
Metadoxine

Brand Name
Alcoliv

Dosage Strength
500 mg per tablet

Packaging
10 tablets per blister

Manufacturer
Sun Pharma

Drug Class
Hepatoprotective / Detoxificant

Composition
Metadoxine (Pyridoxine + PCA)

Primary Use
Alcoholic liver disease, hangover, enzyme control

🎯 Why Choose Alcoliv by Sun Pharma?

⚡

Rapid Alcohol Clearance

Accelerates ethanol and acetaldehyde elimination from blood, reducing hangover severity and hepatotoxicity.

🛡️

Liver Cell Protection

Stabilizes hepatocyte membranes, reduces fat accumulation (steatosis), and prevents fibrosis.

📉

Lowers Liver Enzymes

Clinically proven to reduce elevated ALT, AST, and GGT in alcoholic and non-alcoholic fatty liver.

🧠

Craving Reduction

Helps reduce alcohol craving and supports withdrawal management by modulating neurotransmitters.

⚠️

PRIMARY INDICATIONS FOR ALCOLIV 500MG

Alcoliv (Metadoxine) is indicated for:

Alcoholic liver disease (ALD) – acute and chronic
Fatty liver (hepatic steatosis) – alcoholic and non-alcoholic
Acute alcohol intoxication – speeds up sobering and reduces toxicity
Hangover syndrome – accelerates detoxification
Elevated liver enzymes (ALT/AST/GGT) of various origins
Alcohol withdrawal – reduces craving and withdrawal symptoms

Standard Dosage: 1 tablet twice daily (morning and evening) for 3–6 months depending on severity.
For acute intoxication: 1–2 tablets as a single dose. Always follow medical advice.

🔬 How Metadoxine (Alcoliv) Works

Dual Mechanism

Pyridoxine (Vitamin B6): Essential cofactor for enzymes in amino acid metabolism, neurotransmitter synthesis, and liver detoxification pathways.
Pyrrolidone carboxylate (PCA): Accelerates acetaldehyde dehydrogenase, converting toxic acetaldehyde to acetate, and restores glutathione levels.
Combined effect: Increases hepatic glutathione, reduces oxidative stress, stabilizes hepatocyte membranes, and improves cognitive function.

Pharmacokinetics

Onset of action: 1–2 hours after oral intake
Half-life: 40–60 minutes (rapid elimination)
Excretion: Renal (urine)
Oral bioavailability: 60–80%
Tissue distribution: Highest in liver and kidney

🆚 Metadoxine vs Other Hepatoprotectants

Feature	Metadoxine (Alcoliv)	Silymarin	UDCA
Primary action	Ethanol metabolism acceleration	Antioxidant, anti-inflammatory	Bile acid replacement
Best for	Alcoholic liver disease, hangover	Toxin-induced liver damage	Cholestasis, PBC
Enzyme reduction speed	Rapid (days to weeks)	Moderate (weeks)	Slow (months)
Craving reduction	Yes (alcohol craving)	No	No

Note: Metadoxine is unique in its ability to accelerate alcohol metabolism and reduce acetaldehyde toxicity, making it first-line for alcohol-related liver issues.

📋 Typical Alcoliv Protocols

🍷 Acute Alcohol / Hangover

Acute intoxication: 1–2 tablets as a single dose
Hangover relief: 1 tablet before drinking, 1 tablet after
Detox support: 1 tablet twice daily for 3–7 days
Goal: Rapid acetaldehyde clearance, reduced oxidative stress

🩺 Chronic Liver Disease

Dosage: 500 mg (1 tablet) twice daily
Duration: Minimum 3 months, up to 6 months or longer
Monitor: ALT, AST, GGT every 4–6 weeks
Combine with: abstinence, B-complex, healthy diet

🧪 Elevated Liver Enzymes (non-alcoholic)

Dosage: 500 mg twice daily
Re-evaluate: After 30 days of therapy
Maintenance: 500 mg once daily if enzymes normalize
Important: Address underlying cause (NAFLD, medications, toxins)

✅

Excellent Safety Profile

Alcoliv (Metadoxine) is generally well-tolerated. Rare side effects may include:

Mild gastrointestinal disturbances (nausea, diarrhea) – usually transient
Allergic skin reactions (rash, itching) – very rare
Peripheral neuropathy with prolonged high-dose use (extremely rare, reversible)

Contraindications: Hypersensitivity to metadoxine or any component. Use with caution in pregnancy/lactation only if clearly needed.
No known major drug interactions.

Order Alcoliv 500mg — Metadoxine by Sun Pharma

High-quality hepatoprotective tablets for liver health, alcohol detox, and enzyme control. Manufactured by Sun Pharma.

💊 Metadoxine 500mg

🏭 Sun Pharma

⚡ 10 Tablets/blister

💊 Buy Alcoliv 500mg

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⚠️ Important Medical Information

Metadoxine is a prescription medication in many countries. It is indicated for the treatment of alcoholic liver disease and acute alcohol intoxication.
Off-label use for hangover or general liver protection should be discussed with a healthcare provider.
Not a substitute for alcohol abstinence. If you have liver disease, consult a specialist before use.
Monitor liver function tests regularly during prolonged therapy. This product contains metadoxine 500mg per tablet.
Keep out of reach of children. This information is for educational purposes only and does not replace professional medical advice.

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Additional Information

Tablet's	30, 60, 120

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