Viboliv 500mg

Metadoxine

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Metadoxine 500mg

Viboliv • 10 Tablets per Blister by Dr. Reddy’s
Pharmaceutical-grade hepatoprotective and detoxifying agent by Dr. Reddy’s Laboratories
Accelerates ethanol metabolism • Reduces acetaldehyde toxicity • Protects hepatocytes • Supports recovery in alcoholic liver disease, fatty liver, and enzyme elevation

💊 VIBOLIV (METADOXINE) BY DR. REDDY’S

🏭

Manufactured by Dr. Reddy’s Laboratories

Dr. Reddy’s is a global pharmaceutical leader known for high-quality generics. Viboliv (Metadoxine 500mg) is a
hepatoprotective formulation that combines pyridoxine (Vitamin B6) and pyrrolidone carboxylate (PCA).
It accelerates the elimination of ethanol and acetaldehyde, reduces oxidative stress, and helps restore liver function.

📦 Product Specifications

Generic Name
Metadoxine
Brand Name
Viboliv
Dosage Strength
500 mg per tablet
Packaging
10 tablets per blister
Manufacturer
Dr. Reddy’s Laboratories
Drug Class
Hepatoprotective / Detoxificant
Composition
Metadoxine (Pyridoxine + PCA)
Therapeutic Use
Alcoholic liver disease, fatty liver

🎯 Why Choose Metadoxine (Viboliv)?

Rapid Alcohol Elimination

Accelerates ethanol and acetaldehyde clearance from blood and tissues, reducing hangover severity and toxicity.

🛡️

Liver Cell Protection

Stabilizes hepatocyte membranes, reduces steatosis (fat accumulation), and prevents fibrosis progression.

🧪

Lowers Liver Enzymes

Clinically proven to reduce elevated ALT, AST, and GGT levels in alcoholic and non-alcoholic fatty liver.

🧠

Cognitive Support

Improves attention and memory in patients with alcohol dependence by reducing acetaldehyde brain toxicity.

⚠️

PRIMARY INDICATIONS FOR METADOXINE 500MG

Viboliv is indicated for:

  • Alcoholic liver disease (ALD) – acute and chronic
  • Fatty liver (steatosis) of various origins
  • Drug-induced liver injury (supportive therapy)
  • Hangover syndrome – accelerates detoxification
  • Elevated liver enzymes (ALT/AST/GGT)
  • Alcohol withdrawal – reduces craving and withdrawal symptoms

Dosage: Typically 1 tablet twice daily (morning and evening) for 3-6 months depending on severity.
For acute alcohol intoxication: 1-2 tablets as a single dose. Always follow medical advice.

🔬 How Metadoxine Works

Dual Action Mechanism

  • Pyridoxine (Vitamin B6): Cofactor for enzymes involved in amino acid metabolism and neurotransmitter synthesis; essential for liver detox pathways.
  • Pyrrolidone carboxylate (PCA): Accelerates acetaldehyde dehydrogenase activity, speeding up conversion of toxic acetaldehyde to acetate.
  • Combined effect: Increases hepatic glutathione, reduces oxidative stress, and stabilizes cell membranes.

Key Pharmacokinetics

  • Onset of action: 1-2 hours after oral intake
  • Half-life: 40-60 minutes (rapidly acting)
  • Excretion: Renal (urine)
  • Bioavailability: 60-80% after oral administration
  • Tissue distribution: Highest concentrations in liver and kidney

🆚 Metadoxine vs Other Hepatoprotectants

Property Metadoxine (Viboliv) Silymarin (Milk Thistle) UDCA
Primary action Ethanol metabolism acceleration Antioxidant, anti-inflammatory Bile acid replacement
Best for Alcoholic liver disease, hangover Toxin-induced liver damage Cholestasis, PBC
Enzyme reduction speed Rapid (days to weeks) Moderate (weeks) Slow (months)
Addiction support Reduces alcohol craving No No

Note: Metadoxine is particularly effective when alcohol is still in the system, making it unique among hepatoprotectants.

📋 Typical Viboliv Protocols

🍷 Active Drinking / Hangover

  • Acute intoxication: 1-2 tablets as single dose
  • Hangover prevention: 1 tablet before drinking, 1 tablet after
  • Detox support: 1 tablet twice daily for 3-7 days
  • Goal: Rapid acetaldehyde clearance

🩺 Chronic Liver Disease

  • Dosage: 500 mg (1 tablet) twice daily
  • Duration: Minimum 3 months, up to 6 months
  • Monitor: ALT, AST, GGT every 4-6 weeks
  • Combine with: abstinence, B-complex, lifestyle changes

🧪 Elevated Liver Enzymes (non-alcoholic)

  • Dosage: 500 mg twice daily
  • Evaluation: Recheck enzymes after 30 days
  • Maintenance: 500 mg once daily if enzymes normalize
  • Note: Address underlying cause (diet, meds, toxins)

Excellent Safety Profile

Metadoxine is generally well-tolerated. Rare side effects may include:

  • Mild gastrointestinal disturbances (nausea, diarrhea) – usually transient
  • Allergic skin reactions (rash, itching) – very rare
  • Peripheral neuropathy with prolonged high-dose use (extremely rare)

Contraindications: Hypersensitivity to any component. Use with caution in pregnancy/lactation only if clearly needed.
No known major drug interactions.

Order Viboliv 500mg — Metadoxine by Dr. Reddy’s

High-quality hepatoprotective tablets for liver health, alcohol detox, and enzyme control. Manufactured by Dr. Reddy’s.

💊 Metadoxine 500mg
🏭 Dr. Reddy’s
⚡ 10 Tablets/blister

💊 Buy Viboliv 500mg

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⚠️ Important Medical Information

Metadoxine is a prescription medication in many countries. It is indicated for the treatment of alcoholic liver disease and acute alcohol intoxication.
Off-label use for hangover or general liver protection should be discussed with a healthcare provider.
Not a substitute for alcohol abstinence. If you have liver disease, consult a specialist before use.
Monitor liver function tests regularly during prolonged therapy. This product contains metadoxine 500mg per tablet.
Keep out of reach of children. This information is for educational purposes only and does not replace professional medical advice.

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