โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Meloxicam |
|---|---|
| ๐ Indication: | Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis |
| ๐บ๐ธ US Brand: | Mobic |
| ๐ญ Manufacturer: | Johnlee Pharmaceuticals Pvt. Ltd. (Founded: 2005) |
| ๐ฆ Packaging: | 10 Tablets per Strip |
| ๐งช Strength: | 15 mg |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What is Meloxicam 15 mg (Melorise)?
Melorise provides a 15 mg dose of Meloxicam, a preferential COX-2 inhibitor that reduces inflammation and pain in chronic arthritic conditions. By targeting COX-2 more than COX-1, Meloxicam offers effective symptomatic relief with a lower risk of gastrointestinal ulceration compared to non-selective NSAIDs.
Clinical trials show that Meloxicam 15 mg once daily significantly improves joint function and reduces pain scores within 1โ2 weeks. Its long half-life allows convenient once-daily dosing, enhancing patient adherence.
For complete prescribing and safety information, refer to the FDA label for Mobic and the Drugs.com monograph. Additional guidance is available through the NHS Medicines AโZ entry and the WHO Essential Medicines List.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C14H13N3O4S |
| Molecular Weight | 351.4 g/mol |
| Bioavailability | ~89% |
| Metabolism | Hepatic (CYP2C9) |
| Half-Life | ~20 hours |
Meloxicam preferentially inhibits COX-2, decreasing prostaglandin synthesis in inflamed tissues while sparing gastric mucosa.
๐ก Indications & Dosing
| Condition | Dose |
|---|---|
| Osteoarthritis & Rheumatoid Arthritis | 15 mg once daily |
| Ankylosing Spondylitis | 15 mg once daily |
| Acute Pain (off-label) | 15 mg as needed (short-term use) |
Take with food or milk to reduce GI upset. Do not exceed 15 mg daily.
โ ๏ธ Warnings & Side Effects
Common:
- Dyspepsia, nausea
- Headache, dizziness
- Edema
Serious:
- Cardiovascular events (MI, stroke)
- GI bleeding or ulcers
- Renal impairment
Use the lowest effective dose for the shortest duration. Monitor blood pressure, renal function, and GI symptoms regularly.
๐ฅ Storage Instructions
Store at 20โ25ยฐC in original blister pack. Protect from moisture and light. Keep out of reach of children.
๐ Availability & Purchasing
- USA: Prescription-only (Mobic); generics available.
- UK & EU: Prescription required; Meloxicam generics.
- Australia: Prescription and TGA approval for import.
Importing from India can reduce costs; ensure compliance with regulations and valid prescription.
๐ Related NSAID Therapies
- Naproxen SR 750 mg โ sustained-release naproxen.
- Celecoxib 200 mg โ COX-2 selective inhibitor.
- Piroxicam 20 mg โ long-acting NSAID.
๐ฅ Educational Video on Meloxicam
๐จโโ๏ธ Expert Insight: Dr. Anjali Verma, Rheumatologist
โMeloxicamโs preferential COX-2 inhibition profile provides effective pain relief in arthritis with a better GI safety margin. Once-daily dosing enhances adherence.โ





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